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Article
Open AccessValidation of a novel model for the early detection of hepatocellular carcinoma
The biomarkers alpha-fetoprotein (AFP) and protein induced by vitamin K absence/antagonist-II (PIVKA-II) may be useful for detecting early-stage hepatocellular carcinoma (HCC). We evaluated the performance of ...
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Article
Open AccessGenetic editing of HLA expression in hematopoietic stem cells to broaden their human application
Mismatch of human leukocyte antigens (HLA) adversely impacts the outcome of patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT). This translates into the clinical requirement to timely...
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Article
Open AccessThe genome of Mesobuthus martensii reveals a unique adaptation model of arthropods
Representing a basal branch of arachnids, scorpions are known as ‘living fossils’ that maintain an ancient anatomy and are adapted to have survived extreme climate changes. Here we report the genome sequence of M...
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Article
Isolation and identification of a novel cDNA that encodes human yrdC protein
In the course of detecting the interaction protein of RBBP10 by yeast two-hybridization, we isolated a novel cDNA that encodes a putative human protein with yrdC domain. It is named human yrdC protein. Because...