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  1. Article

    Open Access

    SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy

    SETD2 protects against genomic instability via maintenance of homologous recombination repair (HRR) and mismatch repair (MMR) in neoplastic cells. However, it remains unclear whether SETD2 dysfunction is a comple...

    **aobin Zheng, **g Lin, Jiani **ong, Yanfang Guan, Bin Lan, Yi Li, Xuan Gao… in BMC Cancer (2023)

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  2. Article

    Open Access

    Clonal evolution analyses of a chronic myeloid leukemia patient with hematopoietic stem cell transplantation based on deep sequencing

    The Philadelphia (Ph) chromosome is the hallmark chromosome aberration in chronic myeloid leukemia (CML), which confers the cancer phenotype of the disease. However, how the Ph chromosome forms and the genetic...

    Fuhua Yang, ** Wang, Jia Wan, **aoqing Jia, An Zhou… in Holistic Integrative Oncology (2023)

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  3. No Access

    Article

    Preparation of a novel EGFR specific immunotoxin and its efficacy of anti-colorectal cancer in vitro and in vivo

    Epithelial growth factor receptor (EGFR), as a malignancy marker, is overly expressed in multiple solid tumors including colorectal neoplasms, one of the most prevalent malignancies worldwide. The main objecti...

    Shuifa Wu, Cuimin Deng, Caiyun Zhang, Jiani **ong… in Clinical and Translational Oncology (2021)

  4. No Access

    Article

    CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma

    CircRNAs play essential roles in various physiological processes and involves in many diseases, in particular cancer. Global downregulation of circRNA expression has been observed in hepatocellular carcinoma (...

    Xueying Wang, Jiani Dong, **ao**g Li, Zeneng Cheng, Qubo Zhu in Oncogene (2021)