4 Result(s)

Article

YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor

YAP is a transcriptional co-regulator that plays important roles in various patho-physiological processes, including the survival and death of cells. However, the effect of YAP on apoptosis and EMT, simultaneo...

Yi Liu, Kai He, Ying Hu, **aojie Guo, Dongmei Wang, Weiwei Shi… in Scientific Reports (2017)

Article

FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers

The forkhead box transcription factor A2 (FOXA2) is an important regulator in animal development and body homeostasis. However, whether FOXA2 is involved in transforming growth factor β1 (TGF-β1)-mediated epit...

Yunneng Tang, Guangwen Shu, **nwang Yuan, Naihe **g, Jianguo Song in Cell Research (2011)

Article

Protein kinase A suppresses the differentiation of 3T3-L1 preadipocytes

cAMP and protein kinase A (PKA) are widely known as signaling molecules that are important for the induction of adipogenesis. Here we show that a strong increase in the amount of cAMP inhibits the adipogenesis...

Fuqiang Li, Dongmei Wang, Yiran Zhou, Bo Zhou, Yanan Yang, Hehua Chen… in Cell Research (2008)

Article

EMT or apoptosis: a decision for TGF-β

Jianguo Song in Cell Research (2007)