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  1. Article

    Open Access

    Harnessing three-dimensional porous chitosan microsphere embedded with adipose-derived stem cells to promote nerve regeneration

    Nerve guide conduits are a promising strategy for reconstructing peripheral nerve defects. Improving the survival rate of seed cells in nerve conduits is still a challenge and microcarriers are an excellent th...

    Yaqiong Zhu, Dan Yi, **g Wang, Yongyi Zhang, Molin Li in Stem Cell Research & Therapy (2024)

  2. Article

    Open Access

    Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury

    Various immune cells and cytokines are present in the aftermath of peripheral nerve injuries (PNI), and coordination of the local inflammatory response is of great significance for the recovery of PNI. Mesench...

    **angling Li, Yanjun Guan, Chaochao Li, Tieyuan Zhang in Stem Cell Research & Therapy (2022)

  3. Article

    Open Access

    Functional tissue-engineered microtissue formed by self-aggregation of cells for peripheral nerve regeneration

    Peripheral nerve injury (PNI) is one of the essential causes of physical disability with a high incidence rate. The traditional tissue engineering strategy, Top-Down strategy, has some limitations. A new tissu...

    Jian Zhang, Chaochao Li, Fanqi Meng, Yanjun Guan in Stem Cell Research & Therapy (2022)

  4. Article

    Open Access

    Ultrasound-guided platelet-rich plasma injection and multimodality ultrasound examination of peripheral nerve crush injury

    Ultrasound-guided platelet-rich plasma (PRP) injection is able to make up for the limitations of applying a single growth factor. The goal of this study was to investigate the effects of serial ultrasound-guid...

    Yaqiong Zhu, Zhuang **, **g Wang, Siming Chen, Yongqiang Hu in npj Regenerative Medicine (2020)

  5. Article

    Open Access

    Co-culture of hWJMSCs and pACs in double biomimetic ACECM oriented scaffold enhances mechanical properties and accelerates articular cartilage regeneration in a caprine model

    The dedifferentiation of chondrocytes and the unstable chondrogenic differentiation status of pluripotent mesenchymal stem cells (MSCs) are immense issues in cell-based articular cartilage repair and regenerat...

    Yu Zhang, Chunxiang Hao, Weimin Guo, **aoyu Peng in Stem Cell Research & Therapy (2020)

  6. Article

    Open Access

    The optimal time to inject bone mesenchymal stem cells for fracture healing in a murine model

    Bone marrow is an important source of stem cells, which can promote bone fracture healing.

    **n Wang, Cheng Wang, Wenlong Gou, **aolong Xu, Yu Wang in Stem Cell Research & Therapy (2018)

  7. Article

    Open Access

    Stem cell therapy for treating osteonecrosis of the femoral head: From clinical applications to related basic research

    Osteonecrosis of the femoral head (ONFH) is a refractory disease that is associated with collapse of the femoral head, with a risk of hip arthroplasty in younger populations. Thus, there has been an increased ...

    Rui Li, Qiu-**a Lin, Xue-Zhen Liang, Guang-Bo Liu, He Tang in Stem Cell Research & Therapy (2018)

  8. Article

    Open Access

    Differentiation of adipose-derived stem cells into Schwann cell-like cells through intermittent induction: potential advantage of cellular transient memory function

    Peripheral nerve injury (PNI) is a worldwide issue associated with severe social and economic burden. Autologous nerve grafting, the gold standard treatment for peripheral nerve defects, still has a number of ...

    Xun Sun, Yun Zhu, He-yong Yin, Zhi-yuan Guo, Feng Xu in Stem Cell Research & Therapy (2018)

  9. Article

    Open Access

    Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity

    MicroRNAs have an important role in bone homeostasis. However, the detailed mechanism of microRNA-mediated intercellular communication between bone cells remains elusive. Here, we report that osteoclasts secre...

    Weijia Sun, Chenyang Zhao, Yuheng Li, Liang Wang, Guangjun Nie in Cell Discovery (2016)