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  1. Article

    Open Access

    The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome

    The pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a role for hydrogen sulfide (H2S) in pain sign...

    Guang-Yin Xu, John H Winston, Mohan Shenoy, Shufang Zhou, Jiande DZ Chen in Molecular Pain (2009)