Skip to main content

2 Result(s)

within Jianbin Ruan Remove this filter Life Sciences Remove this filter

and

  1. Article

    Regulating GSDMB pore formation: to ignite or inhibit?

    In the recent Nature, Wang et al. and Zhong et al. present the cryo-EM structures of Gasdermin B (GSDMB) pore and strucures of GSDMB in complex with a Shigella effector, IpaH7.8. The structures shed light on the ...

    Jianbin Ruan in Cell Death & Differentiation (2023)

    Download PDF (530 KB) View Article

  2. Article

    Open Access

    Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2

    Absent in melanoma 2 (AIM2) is an essential cytosolic double-stranded DNA receptor that assembles with the adaptor, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and caspa...

    Alvin Lu, Yang Li, Qian Yin, Jianbin Ruan, **ong Yu, Edward Egelman… in Cell Discovery (2015)

    Download PDF (4495 KB) View Article