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  1. Article

    Open Access

    Case report: primary resistance to osimertinib in erlotinib-pretreated lung adenocarcinoma with EGFR T790 M mutation

    Among non-small cell lung cancer (NSCLC) patients with acquired T790 M mutation resistance to first-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), 71% are likely to benefit f...

    Lin-Peng Zheng, Li-Ying Chen, **ng-Yun Liao, Zi-Han Xu, Zheng-Tang Chen in BMC Cancer (2018)

  2. Article

    Open Access

    Essential role of miR-200c in regulating self-renewal of breast cancer stem cells and their counterparts of mammary epithelium

    Breast cancer stem cells (BCSCs) have been reported as the origin of breast cancer and the radical cause of drug resistance, relapse and metastasis in breast cancer. BCSCs could be derived from mutated mammary...

    Zhong-Ming Feng, Jun Qiu, **e-Wan Chen, Rong-**a Liao, **ng-Yun Liao in BMC Cancer (2015)