101 Result(s)
within
English
Life Sciences
Jian-** Cao
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Article
Open AccessHierarchical modularity of nested bow-ties in metabolic networks
The exploration of the structural topology and the organizing principles of genome-based large-scale metabolic networks is essential for studying possible relations between structure and functionality of metab...
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Open AccessModular co-evolution of metabolic networks
The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known functional modules. However, how the modula...
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Open AccessEvolutional selection of a combinatorial phage library displaying randomly-rearranged various single domains of immunoglobulin (Ig)-binding proteins (IBPs) with four kinds of Ig molecules
Protein A, protein G and protein L are three well-defined immunoglobulin (Ig)-binding proteins (IBPs), which show affinity for specific sites on Ig of mammalian hosts. Although the precise functions of these m...
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Open AccessDetoxification of Gramine by the Cereal Aphid Sitobion avenae
Secondary metabolites play an important role in host plant resistance to insects, and insects, in turn, may develop mechanisms to counter plant resistance mechanisms. In this study, we investigated the toxicit...
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Open AccessHelicobacter pylori infection is associated with decreased serum levels of high density lipoprotein, but not with the severity of coronary atherosclerosis
The objective of this survey was to study the association between Helicobacter pylori infection and the severity of coronary atherosclerosis.
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The efficacy of FMD vaccine reduced non-structural proteins with a mAb against 3B protein
A monoclonal antibody, 3BIgG, against the prokaryotically expressed foot-and-mouth disease virus (FMDV) non-structural protein (NSP) 3B was obtained. The 3BIgG-sepharose conjugant (3BmAb-6BFF) was prepared by ...
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The mechanisms and possible significance of upregulation of stomatin expression by hypoxia and/or glucocorticoids
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Open AccessGenome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential
Completion of genome sequences for the diploid Setaria italica reveals features of C4 photosynthesis that could enable improvement of the polyploid biofuel crop switchgrass (Panicum virgatum). The genetic basis o...
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Open AccessDihydrotestosterone regulating apolipoprotein M expression mediates via protein kinase C in HepG2 cells
Administration of androgens decreases plasma concentrations of high-density lipid cholesterol (HDL-C). However, the mechanisms by which androgens mediate lipid metabolism remain unknown. This present study use...
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Open AccessCharacterization and differential expression of microRNAs in the ovaries of pregnant and non-pregnant goats (Capra hircus)
Ovarian follicular development and hormone secretion are complex and coordinated biological processes which will usually be altered during pregnancy. Ovarian function is tightly regulated by a multitude of gen...
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Open AccessGlobal transcriptome profiles of Camellia sinensis during cold acclimation
Tea is the most popular non-alcoholic health beverage in the world. The tea plant (Camellia sinensis (L.) O. Kuntze) needs to undergo a cold acclimation process to enhance its freezing tolerance in winter. Change...
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Open AccessAn ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants
Abscisic acid (ABA) is the most important hormone for plants to resist drought and other abiotic stresses. ABA binds directly to the PYR/PYL family of ABA receptors, resulting in inhibition of type 2C phosphat...
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Open AccessPeach genetic resources: diversity, population structure and linkage disequilibrium
Peach (Prunus persica (L.) Batsch) is one of the most important model fruits in the Rosaceae family. Native to the west of China, where peach has been domesticated for more than 4,000 years, its cultivation sprea...
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Open AccessEfficient genome editing in plants using a CRISPR/Cas system
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LC-MS/MS determination of colistin in Mueller–Hinton broth for in vitro pharmacodynamic studies
A rapid and simple method was developed and validated for the determination of colistin A and B in Mueller–Hinton broth using LC-tandem MS. Both analyte and internal standard (IS) (polymyxin B1) were determine...
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Open AccessSequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement
Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.
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Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear memory
The N-methyl-D-aspartate receptor (NMDAR) in adult forebrain is a heterotetramer mainly composed of two GluN1 subunits and two GluN2A and/or GluN2B subunits. The synaptic expression and relative numbers of Glu...
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Open AccessIsolation, identification and genomic characterization of the Asian lineage Zika virus imported to China
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Open AccessHuman INO80/YY1 chromatin remodeling complex transcriptionally regulates the BRCA2- and CDKN1A-interacting protein (BCCIP) in cells
The BCCIP (BRCA2- and CDKN1A-interacting protein) is an important cofactor for BRCA2 in tumor suppression. Although the low expression of BCCIP is observed in multiple clinically diagnosed primary tumor tissues s...
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Open AccessExtrasynaptic NMDA receptor-induced tau overexpression mediates neuronal death through suppressing survival signaling ERK phosphorylation
Intracellular accumulation of the hyperphosphorylated tau is a pathological hallmark in the brain of Alzheimer disease. Activation of extrasynaptic NMDA receptors (E-NMDARs) induces excitatory toxicity that is...
