-
Article
Human hepatitis B virus and hepatocellular carcinoma II. Experimental induction of hepatocellular carcinoma in tree shrews exposed to hepatitis B virus and aflatoxin B1
On the basis of the successful establishment of an animal model in tree shrews experimentally infected with human hepatitis B virus (HBV), a study on the hepatocarcinogenic effects of HBV and/or aflatoxin B1 (...
-
Article
Human hepatitis B virus and hepatocellular carcinoma I. Experimental infection of tree shrews with hepatitis B virus
Tree shrews (Tupaia belangeri chinenesis) can be experimentally infected with human hepatitis B virus (HBV) by inoculation with human serum positive for HBV, the experimental infection rate being 55.21%. Successi...
-
Article
Expression of ras gene in experimental hepatocarcinogenesis in tree shrews
Objective: In order to investigate the relationship between the expression of ras gene and the development of hepatocellular carcinoma (HCC). Materials and Methods: The experimental tree shrews were divided into ...
-
Article
Endoscopic Nd:YAG Laser Therapy Combined with Local Chemotherapy of Superficial Carcinomas of the Oesophagus and Gastric Cardia
The aim of this study was to explore the possibilities of non-surgical management for superficial carcinomas of the oesophagus and gastric cardia. Thirty-one patients with superficial oesophageal or gastric c...
-
Article
Detection of SBEM-mRNA in peripheral blood of patients with breast cancer and its clinical significance
The aim of the present study is to explore the expression of a specific marker of breast cancer, small breast epithelial mucin (SBEM) mRNA, in peripheral blood and to investigate its significance.
-
Article
Hashimoto’s encephalopathy mimicking spinocerebellar ataxia
-
Article
Open AccessAssociation analysis between HOXD9 genes and the development of developmental dysplasia of the hip in Chinese female Han population
Developmental dysplasia of the hip (DDH) is a congenital or acquired deformation or misalignment of the hip joint which affects mainly females. We hypothesized that HOXD9 gene could be regulated in acetabular siz...
-
Article
Application of ex vivo 1H NMR metabonomics to the characterization and possible detection of renal cell carcinoma metastases
Renal cell carcinoma (RCC) is the most prevalent malignancy of the kidney. Its survival rates are very low since most of patients develop metastases beyond the kidney at the time of diagnosis. Early detection ...
-
Article
Telbivudine myopathy in a patient with chronic hepatitis B
Case A 25-year-old man with hepatitis B virus (HBV) infection received antiviral treatment with telbivudine 600 mg daily. Six months after starting treatment, the patient developed progressive we...
-
Article
Open AccessHashimoto’s encephalopathy cases: Chinese experience
Hashimoto’s encephalopathy is a poorly understood syndrome consisting of heterogeneous neurological symptoms and high serum antithyroid antibody titers, typically responding to steroids. More clinical series s...
-
Article
Open AccessIntraocular pressure vs intracranial pressure in disease conditions: A prospective cohort study (Bei**g iCOP study)
The correlation between intracranial pressure (ICP) and intraocular pressure (IOP) is still controversial in literature and hence whether IOP can be used as a non-invasive surrogate of ICP remains unknown. The...
-
Article
Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy
The objective of the study is to compare the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) and mini-percutaneous nephrolithotomy (MPCNL) in treating renal stones sizing 15–25 mm in infant...
-
Article
Association studies of 19 candidate SNPs with sporadic Alzheimer’s disease in the North Chinese Han population
Genome-wide association studies (GWAS) identified multiple single-nucleotide polymorphisms (SNPs) that are associated with the pathogenesis of Alzheimer’s disease (AD). As replication in independent studies re...
-
Article
Evaluating the prevalence of dementia in hospitalized older adults and effects of comorbid dementia on patients’ hospital course
Many older adults with dementia are hospitalized for diagnoses other than dementia. We aimed to determine the prevalence of comorbid dementia among hospitalized older adults and evaluate its effects on their h...
-
Article
Intravenous thrombolysis for minor stroke and rapidly improving symptoms: a quantitative overview
Minor stroke and rapidly improving symptoms (MRIS) are usually excluded from intravenous thrombolysis (IVT) considering a possible benign prognosis and potential bleeding risk. However, its risk–benefit profil...
-
Article
Acute kidney injury caused by ceftriaxone-induced urolithiasis in children: a single-institutional experience in diagnosis, treatment and follow-up
To evaluate our clinical outcomes in managing acute kidney injury (AKI) resulting from ceftriaxone-induced urolithiasis with emergency treatment.
-
Article
Anatomical basis of female pelvic cavity for nerve sparing radical hysterectomy
The separation and sparing of the vesical branch of the inferior hypogastric plexus (IHP), to preserve the pelvic autonomic nerve, is critical and difficult in nerve sparing radical hysterectomy. Pelvic local ...
-
Article
Open AccessThe efficacy of Cognitive training in patients with VAsCular Cognitive Impairment, No dEmentia (the Cog-VACCINE study): study protocol for a randomized controlled trial
Vascular cognitive impairment, no dementia (VCIND) refers to cognitive deficits associated with underlying vascular causes that fall short of a dementia diagnosis. There is currently no treatment for VCIND. Co...
-
Article
Open AccessMonetary costs of Alzheimer’s disease in China: protocol for a cluster-randomised observational study
Alzheimer’s disease (AD) is the most common type of dementia. International multilateral cost-of-illness (COI) studies have revealed that the cost of treating this disease is huge, which places a significant b...
-
Article
Open AccessAssessment of intracranial pressure with ultrasonographic retrobulbar optic nerve sheath diameter measurement
Ultrasonograpic retrobulbar optic nerve sheath diameter (ONSD) measurement is considered to be an alternative noninvasive method to estimate intracranial pressure,but the further validation is urgently needed....