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Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients

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  1. Article

    Open Access

    The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study

    Regional block, such as thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), or serratus anterior plane block (SAPB) has been recommended to reduce postoperative opioid use in recent guideli...

    Yan **ang, Liang Chen, Jiang Jia, Fu Yili in Journal of Cardiothoracic Surgery (2024)

  2. Article

    Open Access

    Correction: Cost-effectiveness analysis of digital therapeutics for home-based cardiac rehabilitation for patients with chronic heart failure: model development and data analysis

    Tianyi Liu, Yiyang Zhan, Silei Chen in Cost Effectiveness and Resource Allocation (2024)

  3. Article

    Open Access

    Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways

    Mechanical ventilation can cause acute atrophy and injury in the diaphragm, which are related to adverse clinical results. However, the underlying mechanisms of ventilation-induced diaphragm dysfunction (VIDD)...

    Weimin Shen, Ye Jiang, Ying Xu, **aoli Qian, Jianwei Jia in BMC Pulmonary Medicine (2023)

  4. Article

    Open Access

    Increasing serum miR-409-3p predicts the major adverse cardiac adverse events in elderly patients after hip fracture surgery

    Major adverse cardiovascular events (MACE) are critical complications responsible for the morbidity and mortality of elderly hip fracture patients. There was an urgent need to explore an effect biomarker for p...

    Zhengtao Sun, Kai Cheng, Guochao **, Jian Jia in BMC Musculoskeletal Disorders (2023)

  5. Article

    Open Access

    Cost-effectiveness analysis of digital therapeutics for home-based cardiac rehabilitation for patients with chronic heart failure: model development and data analysis

    In recent years, numerous guidelines and expert consensus have recommended the inclusion of digital technologies and products in cardiac rehabilitation. Digital therapeutics (DTx) is an evidence-based medicine...

    Tianyi Liu, Yiyang Zhan, Silei Chen in Cost Effectiveness and Resource Allocation (2023)

  6. Article

    Open Access

    Aberrant palmitoylation caused by a ZDHHC21 mutation contributes to pathophysiology of Alzheimer’s disease

    The identification of pathogenic mutations in Alzheimer’s disease (AD) causal genes led to a better understanding of the pathobiology of AD. Familial Alzheimer’s disease (FAD) is known to be associated with mu...

    Wenwen Li, Yana Pang, Yan Wang, Fan Mei, Mengmeng Guo, Yi** Wei in BMC Medicine (2023)

  7. Article

    Open Access

    PEEP application during mechanical ventilation contributes to fibrosis in the diaphragm

    Positive end-expiratory airway pressure (PEEP) is a potent component of management for patients receiving mechanical ventilation (MV). However, PEEP may cause the development of diaphragm remodeling, making it...

    **aoli Qian, Ye Jiang, Jianwei Jia, Weimin Shen, Yuejia Ding in Respiratory Research (2023)

  8. Article

    Open Access

    Robotic guidance for percutaneous placement of triangular osteosynthesis in vertically unstable sacrum fractures: a single-center retrospective study

    To evaluate the effectiveness and safety of robot-aided percutaneous triangular osteosynthesis combined with close reduction for vertically unstable sacrum fractures (VUSFs).

    Zhao-Jie Liu, Ya Gu, Jian Jia in Journal of Orthopaedic Surgery and Research (2023)

  9. Article

    Open Access

    Comparative retrospective study of triangular osteosynthesis with and without robotic assistance for unilateral unstable sacral fractures combined with lumbosacral junction injuries

    To compare the clinical efficacy of unilateral unstable sacral fractures (USFs) involving the lumbosacral region treated with and without robot-aided triangular osteosynthesis (TOS).

    Zhao-Jie Liu, Ya Gu, Jian Jia in BMC Surgery (2022)

  10. Article

    Open Access

    The Kocher-Langenbeck approach combined with robot-aided percutaneous anterior column screw fixation for transverse-oriented acetabular fractures: a retrospective study

    Transverse-oriented acetabular fractures (TOAFs), including transverse, transverse with posterior wall and T-shaped fractures, are always challenging for double-column reduction and fixation with minimally inv...

    Zhao-jie Liu, Ya Gu, Jian Jia in BMC Musculoskeletal Disorders (2022)

  11. Article

    Open Access

    Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages

    Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease with scantly effective treatment. Numerous evidences indicated that macrophages play an important role in the occurrence and patho...

    **ao Lin, **ao-qin Lei, Jie-ke Yang, Jian Jia in BMC Complementary Medicine and Therapies (2022)

  12. Article

    Open Access

    Development and validation of the nomogram based on INR and eGFR for estimation of mortality in patients with acute-on-chronic hepatitis B liver failure

    Acute-on-chronic hepatitis B liver failure (ACHBLF) is a critical clinical syndrome with a high short-term mortality evolved from chronic hepatitis B (CHB)-related liver disease. Prediction of mortality risk a...

    Shengnan Li, **ehua Zhang, Qian Li, Binyue Lv, Yefan Zhang in BMC Gastroenterology (2021)

  13. Article

    Open Access

    The effect of selective cerebral perfusion on cerebral versus somatic tissue oxygenation during aortic coarctation repair in neonates and infants

    Suboptimal tissue perfusion and oxygenation may be the root cause of certain perioperative complications in neonates and infants having complicated aortic coarctation repair. Practical, effective, and real-tim...

    Li Zhang, Lu Liu, Zhiqiu Zhong, Hengfang **, Jian Jia in BMC Anesthesiology (2021)

  14. Article

    Open Access

    Health seeking behavior and associated factors among individuals with cough in Yiwu, China: a population-based study

    Previous studies have shown that a certain proportion of the population did not seek medical treatment after coughing, and understanding the potential reasons is crucial for disease prevention and control.

    **aoyan Sun, Shuying Luo, Lingqiao Lou, Hang Cheng, Zhen Ye in BMC Public Health (2021)

  15. Article

    Open Access

    TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO

    Sensing of pathogenic nucleic acids by pattern recognition receptors (PRR) not only initiates anti-microbe defense but causes inflammatory and autoimmune diseases. E3 ubiquitin ligase(s) critical in innate res...

    Zhou Yu, Xuelian Li, Ming** Yang in Signal Transduction and Targeted Therapy (2021)

  16. Article

    Open Access

    An analysis of clinical risk factors for adolescent scoliosis caused by spinal cord abnormalities in China: proposal for a selective whole-spine MRI examination scheme

    Approximately 80% of adolescent scoliosis cases are idiopathic, and some non-idiopathic scoliosis cases caused by spinal cord abnormalities are misdiagnosed as idiopathic scoliosis. This study examined the ris...

    Wei Xu, **angyang Zhang, Ying Zhu, **aodong Zhu, Zhikun Li in BMC Musculoskeletal Disorders (2020)

  17. Article

    Open Access

    Inhibition of JAK2/STAT3/SOCS3 signaling attenuates atherosclerosis in rabbit

    Previous studies have indicated that the JAK/STAT signaling pathway is involved in modulating arterial adventitia inflammation response. In this study, we designed experiments to further investigate the effect...

    **lan Yang, Jian Jia, Zhen Yu, Zheng Duanmu, Huiwei He in BMC Cardiovascular Disorders (2020)

  18. Article

    Open Access

    Adult-onset vanishing white matter disease with the EIF2B2 gene mutation presenting as menometrorrhagia

    Vanishing white matter disease (VWMD) is one of the most prevalent inherited leukoencephalopathies, which generally presents in childhood as a progressive disorder while less beginning in adulthood. The presen...

    Cuibai Wei, Qi Qin, Fei Chen, Aihong Zhou, Fen Wang, **umei Zuo, Rong Chen in BMC Neurology (2019)

  19. Article

    Open Access

    Use of Twitter data to improve Zika virus surveillance in the United States during the 2016 epidemic

    Zika virus (ZIKV) is an emerging mosquito-borne arbovirus that can produce serious public health consequences. In 2016, ZIKV caused an epidemic in many countries around the world, including the United States. ...

    Shahir Masri, Jianfeng Jia, Chen Li, Guofa Zhou, Ming-Chieh Lee in BMC Public Health (2019)

  20. Article

    Open Access

    Case report of neonate Pierre Robin sequence with severe upper airway obstruction who was rescued by finger guide intubation

    Pierre Robin Sequence (PRS) patients are known for their triad of micrognathia, glossoptosis, and airway obstruction. Their airway can be a challenge even for the most experienced pediatric anesthesiologist.

    Li Zhang, Jian Fei, Jian Jia, **aohua Shi, Meimin Qu, Hui Wang in BMC Anesthesiology (2019)

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