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    Article

    Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

    Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, ...

    Iain Mathieson, Felix R. Day, Nicola Barban, Felix C. Tropf in Nature Human Behaviour (2023)

  2. Article

    Open Access

    Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

    We conducted genome-wide association studies (GWAS) of relative intake from the macronutrients fat, protein, carbohydrates, and sugar in over 235,000 individuals of European ancestries. We identified 21 unique...

    S. Fleur W. Meddens, Ronald de Vlaming, Peter Bowers in Molecular Psychiatry (2021)

  3. Article

    Open Access

    Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

    Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with...

    A. Mesut Erzurumluoglu, Mengzhen Liu, Victoria E. Jackson in Molecular Psychiatry (2020)

  4. No Access

    Article

    Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

    Macronutrient intake, the proportion of calories consumed from carbohydrate, fat, and protein, is an important risk factor for metabolic diseases with significant familial aggregation. Previous studies have id...

    Jordi Merino, Hassan S. Dashti, Sherly X. Li, Chloé Sarnowski in Molecular Psychiatry (2019)