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  1. Article

    Open Access

    Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood

    Early-life stress in adolescence has a long-lasting influence on brain function in adulthood, and it is mostly recognized as a predisposing factor for mental illnesses, such as anxiety and posttraumatic stress...

    Jia-Hui Deng, Wei Yan, Ying Han, Chen Chen, Shi-Qiu Meng in Scientific Reports (2017)

  2. Article

    Open Access

    Epigenetic modification of PKMζ rescues aging-related cognitive impairment

    Cognition is impacted by aging. However, the mechanisms that underlie aging-associated cognitive impairment are unclear. Here we showed that cognitive decline in aged rats was associated with changes in DNA me...

    Chen Chen, Shi-Qiu Meng, Yan-Xue Xue, Ying Han, Cheng-Yu Sun in Scientific Reports (2016)