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Jia-**n Chen
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Article
Study on Acoustic Emission and Crack Propagation Characteristics of Single-Fissured Sandstone with Different Angles Under Uniaxial Compression
The uniaxial compression tests are conducted on single-fissured sandstone with different angles, and the effect of fissure angle (β) on mechanical properties, acoustic emission (AE) features, crack propagation ch...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Open AccessRefining silicon nitride waveguide quality through femtosecond laser annealing
We present a method for modification of silicon nitride (Si3N4) waveguide resonators using femtosecond laser annealing. The quality (Q) factor of the waveguide resonators can be improved by approximately 1.3 time...
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Open AccessAnalyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk
Hobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of these features contributes to increased PTC aggressiveness remains unc...
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Open AccessATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells
Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...
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Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Open AccessLow-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes
Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming challenges like repetitive sequences. However, the high DNA requirement ( > 1 µg) is prohibitive for small organisms. We develop...
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Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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Interfacial energy-mediated bulk transport across artificial cell membranes
The construction of synthetic cells that exhibit some of the complex behaviors of biological cells is a fundamental challenge. A major bottleneck is the transport of substances across the artificial cell membr...
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Amelioration of habitat since the early Holocene contributed to the origin of agriculture in the farming-pastoral zone of northern China
The origin of agriculture in the farming-pastoral zone of northern China remains in dispute. The central region of the Inner Mongolia Plateau is located in the core area of the farming-pastoral zone; thus, it ...
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Open AccessA tabular data generation framework guided by downstream tasks optimization
Recently, generative models have been gradually emerging into the extended dataset field, showcasing their advantages. However, when it comes to generating tabular data, these models often fail to satisfy the ...
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Undersampling based on generalized learning vector quantization and natural nearest neighbors for imbalanced data
Imbalanced datasets can adversely affect classifier performance. Conventional undersampling approaches may lead to the loss of essential information, while oversampling techniques could introduce noise. To add...
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Open AccessGlobal incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035
To study the historical global incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035.
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Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Dynamic change of metabolic dysfunction-associated steatotic liver disease in patients with hepatitis C virus infection after achieving sustained virologic response with direct-acting antivirals
Information on the dynamics of metabolic dysfunction-associated steatotic liver disease (MASLD) among hepatitis C virus patients achieving sustained virologic response (SVR12) with direct-acting antivirals (DAAs)...
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Article
An Analytical Model of Horizontal-Vertical Geogrid Reinforced Foundation
This paper proposed a theoretical solution to predict the bearing capacity of a new horizontal-vertical (H-V) geogrid reinforced foundation under strip footing, incorporating the key mechanism including the fr...
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Article
Efficacy and safety of Ruxolitinib, Crisaborole, and Tapinarof for mild-to-moderate atopic dermatitis: a Bayesian network analysis of RCTs
Given the lack of head-to-head studies of novel non-steroidal molecule topical therapies in mild-to-moderate atopic dermatitis (AD), network meta-analyses (NMAs) can provide comparative efficacy and safety dat...
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ASO Author Reflections: The Clinical Use of Dual-Region Radiomics-Based Machine Learning in the Identification of Subcarinal Lymph Node Metastasis of Non-small Cell Lung Cancer
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A differential privacy-preserving federated learning scheme with predictive maintenance of wind turbines based on deep learning for feature compression and anomaly detection with state assessment
The transport and supply of traditional energy have been greatly affected, which has attracted the attention of countries worldwide and has become an urgent issue. Limited by its own traditional energy shortag...
