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Jia **g
Life Sciences
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Article
Beauveria bassiana (Ascomycota: Hypocreales) spores carried by Scleroderma guani (Hymenoptera: Bethylidae): a novel strategy for improving the control efficiency of Semanotus bifasciatus (Coleoptera: Cerambycidae) in the field
One common biocontrol strategy employed to combat the wood borer Semanotus bifasciatus Motschulsky (the Chinese fir borer, CFB) is the release of parasitic wasps, specifically Sclerodermus guani **ao et Wu. Howev...
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Open AccessThe influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The differences in sex chromosomes are fundamental to the presence of...
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Open AccessNeutrophil-derived migrasomes are an essential part of the coagulation system
Migrasomes are organelles that are generated by migrating cells. Here we report the key role of neutrophil-derived migrasomes in haemostasis. We found that a large number of neutrophil-derived migrasomes exist...
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Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Open AccessStructural basis of tethered agonism and G protein coupling of protease-activated receptors
Protease-activated receptors (PARs) are a unique group within the G protein-coupled receptor superfamily, orchestrating cellular responses to extracellular proteases via enzymatic cleavage, which triggers intr...
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Open AccessHeritability of functional gradients in the human subcortico-cortical connectivity
The human subcortex plays a pivotal role in cognition and is widely implicated in the pathophysiology of many psychiatric disorders. However, the heritability of functional gradients based on subcortico-cortic...
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Open AccessA RsrC-RsrA-RsrB transcriptional circuit positively regulates polysaccharide-degrading enzyme biosynthesis and development in Penicillium oxalicum
Filamentous fungi produce polysaccharide-degrading enzymes, which is controlled by poorly understood transcriptional circuits. Here we show that a circuit comprising RsrC-RsrA-RsrB (Rsr: production of raw-starch-...
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Open AccessLight signaling regulates root-knot nematode infection and development via HY5-SWEET signaling
Meloidogyne incognita is one of the most important plant-parasitic nematodes and causes tremendous losses to the agricultural economy. Light is an important living factor for plants and pathogenic organisms, and ...
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Open AccessDevelopment of a prognostic risk model of uveal melanoma based on N7-methylguanosine-related regulators
Uveal melanoma (UVM) stands as the predominant type of primary intraocular malignancy among adults. The clinical significance of N7-methylguanosine (m7G), a prevalent RNA modifications, in UVM remains unclear.
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Pathophysiological role of Na–Cl cotransporter in kidneys, blood pressure, and metabolism
The Na–Cl cotransporter (NCC) is a well-recognized regulator of ion transportation in the kidneys that facilitates Na+ reabsorption in the distal convoluted tubule. It is also the pharmacologic inhibitory target ...
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Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer’s disease
Recent expansion of proteomic coverage opens unparalleled avenues to unveil new biomarkers of Alzheimer’s disease (AD). Among 6,361 cerebrospinal fluid (CSF) proteins analysed from the ADNI database, YWHAG per...
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Soil Total Nitrogen Mediated the Impact of Climatic Factors on Urban Soil Organic Matter Under Different Land Uses
The **ong'an New Area (XNA) is a nationally designated region characterized by prominent emerging trends, intensive human activities, and rapid urbanization. However there needs to be more clarity regarding th...
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Open AccessUnderstanding the responses of tillering to 2,4-D isooctyl ester in Setaria viridis L.
Green foxtail [Setaria viridis (L.)] is one of the most abundant and troublesome annual grass weeds in alfalfa fields in Northeast China. Synthetic auxin herbicide is widely used in agriculture, while how auxin h...
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Open AccessNano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources
At present, heat stress (HS) has become a key factor that impairs broiler breeding industry, which causes growth restriction and poor meat quality of broilers. Selenium (Se) is an excellent antioxidant and pla...
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Open AccessThe combination of temozolomide and perifosine synergistically inhibit glioblastoma by impeding DNA repair and inducing apoptosis
Temozolomide (TMZ) is widely utilized as the primary chemotherapeutic intervention for glioblastoma. However, the clinical use of TMZ is limited by its various side effects and resistance to chemotherapy. The ...
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Open AccessChanges in the gut microbiota induced by an oral formulation of multiple peptides and plants contribute to its antihypertensive effects
The homeostasis of the gut microbiota is a crucial factor in regulating peripheral and central blood pressure. Formulating a food-derived mixture of antioxidants, anti-inflammatory compounds and prebiotics to ...
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Cold tolerance SNPs and candidate gene mining in the soybean germination stage based on genome-wide association analysis
Three QTLs associated with low-temperature tolerance were identified by genome-wide association analysis, and 15 candidate genes were identified by haplotype analysis and gene expression analyses.
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Open AccessTracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach
The “hologenome” concept is an increasingly popular way of thinking about microbiome-host for marine organisms. However, it is challenging to track hologenome dynamics because of the large amount of material, ...
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Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist
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Open AccessHoney bee (Apis cerana) queen rearing methods influence queen morphological characteristics and reproductive related gene expression
The quality of the queen is crucial for the survival and growth of honey bee colonies. There have been studies related to raising queens with excellent performance since the invention of artificial queen reari...
