33 Result(s)
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Article
Global meat consumption driver analysis with machine learning methods
The growing global meat consumption has serious consequences on human health, the environment and ultimately impacts global food security. Therefore, identifying the drivers of meat consumption and predicting ...
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Article
Open AccessAntiviral and anti-inflammatory activities of chemical constituents from twigs of Mosla chinensis Maxim
Seven undescribed compounds, including three flavones (1–3), one phenylpropanoid (19), three monoaromatic hydrocarbons (27–29), were isolated from the twigs of Mosla chinensis Maxim together with twenty-eight kno...
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Article
Open AccessInsights into chloroplast genome evolution in Rutaceae through population genomics
Chloroplast genomes, pivotal for understanding plant evolution, remain unexplored in Rutaceae, a family with key perennial crops like citrus. Leveraging next-generation sequencing data from 509 Rutaceae access...
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Article
Open AccessInteraction mechanism between luteoloside and corn silk glycans and the synergistic role in hypoglycemic activity
As the two most principal active substances in the corn silk, polysaccharides and flavonoids, the mechanism of interaction between them has been a topic of intense research. This study provides an in-depth inv...
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Article
Open AccessNarciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells
DNA topoisomerases are essential nuclear enzymes in correcting topological DNA errors and maintaining DNA integrity. Topoisomerase inhibitors are a significant class of cancer chemotherapeutics with a definite...
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Article
Open AccessNew halimane and clerodane diterpenoids from Croton cnidophyllus
Three new halimane furanoditerpenoids (1–3) and three new clerodane furanoditerpenoids (4–6), along with seven known terpenoids including four pimarane diterpenoids (7–10) and three norisoprenoids (11–13) were is...
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Article
Open AccessTraditional Chinese medicine Euodiae Fructus: botany, traditional use, phytochemistry, pharmacology, toxicity and quality control
Euodiae Fructus, referred to as “Wuzhuyu” in Chinese, has been used as local and traditional herbal medicines in many regions, especially in China, Japan and Korea, for the treatment of gastrointestinal disord...
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Article
Open AccessIndole alkaloids of Alstonia scholaris (L.) R. Br. alleviated nonalcoholic fatty liver disease in mice fed with high-fat diet
Alstonia scholaris (L.) R. Br (Apocynaceae) is a well-documented medicinal plant for treating respiratory diseases, liver diseases and diabetes traditionally. The current study aimed to investigate the effects of...
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Article
Open AccessThree new pyrrole alkaloids from the endophytic fungus Albifimbria viridis
Three new pyrrole alkaloids albifipyrrols A–C (1–3), were isolated from the endophytic fungus Albifimbria viridis collected from the Chinese medicinal plant. Their structures were elucidated by extensive NMR and ...
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Article
Open AccessNew Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch
One new Daphniphyllum alkaloid, daphnioldhanol A (1), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic metho...
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Article
Open AccessFour New Phloroglucinol-Terpene Adducts from the Leaves of Myrciaria cauliflora
Myrcauones A–D (1–4), four new phloroglucinol–terpene adducts were isolated from the leaves of Myrciaria cauliflora. Their structures with absolute configurations were elucidated by combination of spectroscopic a...
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Article
Open AccessAcute and Sub-chronic Toxicity of Indole Alkaloids Extract from Leaves of Alstonia scholaris (L.) R. Br. in Beagle Dogs
Alstonia scholaris (L.) R. Br., an evergreen tropical plant rich in indole alkaloids with significant physiological activity, is traditionally used to treat respiratory diseases in China. This study was conducted...
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Article
Open AccessGenotoxicity and Safety Pharmacology Studies of Indole Alkaloids Extract from Leaves of Alstonia scholaris (L.) R. Br.
Indole alkaloids extract (IAAS) was prepared from leaves of Alstonia scholaris (L.) R. Br., an evergreen tropical plant widely distributed throughout the world. This plant has been used historically by the Dai et...
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Article
Open AccessAcute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats
Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated. I...
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Article
Open AccessAlkaloid Constituents of Ficus hispida and Their Antiinflammatory Activity
Four new alkaloids, ficuhismines A–D (1–4), together with three known ones, were isolated from Ficus hispida. Their structures were elucidated by spectroscopic analysis and chemical method. The new compounds repr...
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Protocol
A Method for Extraction and LC-MS-Based Identification of Carotenoid-Derived Dialdehydes in Plants
We developed a chemical derivatization based ultra-high performance liquid chromatography-hybrid quadrupole-Orbitrap mass spectrometer (UHPLC-Q-Orbitrap MS) analytical method to identify low-abundant and insta...
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Article
Open AccessAnti-inflammatory and Cytotoxic Triterpenes from the Rot Roots of Panax notoginseng
Four new protopanaxatriol-type triterpenes (1–2) and glucosides (3–4), were isolated from the rot roots of Panax notoginseng (Burk.) Chen, along with four known ones (5–8). Their structures were elucidated on the...
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Article
Open AccessApplication of Metabolomics in the Study of Natural Products
LC–MS-based metabolomics could have a major impact in the study of natural products, especially in its metabolism, toxicity and activity. This review highlights recent applications of metabolomics approach in ...
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Article
Open AccessResearch of Panax spp. in Kunming Institute of Botany, CAS
Panax, a genus of the Araliaceae family, is an important herbal group in traditional Chinese medicine (TCM). Nine species and three varieties are included in the genus of Panax, in which nearly all species have b...
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Article
Open AccessLycoplanines B-D, Three Lycopodium Alkaloids from Lycopodium complanatum
A novel C17N Lycopodium alkaloid (LA), lycoplanine B (1), containing an unusual formyl group, along with two new LAs, lycoplanines C (2) and D (3), were isolated from the whole plant of Lycopodium complanatum. Th...
