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Open AccessSignificance of headache in intracranial vertebrobasilar artery dissections: an observational study
Headache may represent acute phase of intracranial vertebrobasilar artery dissection (iVBAD). We aimed to evaluate its clinical significance in iVBAD. Consecutive acute iVBAD patients were grouped into rupture...
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Article
Open AccessSpider-inspired tunable mechanosensor for biomedical applications
The recent advances of wearable sensors are remarkable but there are still limitations that they need to be refabricated to tune the sensor for target signal. However, biological sensory systems have the inher...
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Article
A Deep Learning-Based Automatic Collateral Assessment in Patients with Acute Ischemic Stroke
This study aimed to develop a supervised deep learning (DL) model for grading collateral status from dynamic susceptibility contrast magnetic resonance perfusion (DSC-MRP) images from patients with large vesse...
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Aperiodic alternating nystagmus in adult-onset Alexander disease with a novel mutation
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Open AccessSimultaneous monitoring of the middle cerebral and basilar arteries to detect right-to-left shunts using transcranial Doppler by agitated saline administration
Transcranial Doppler (TCD) is an easy, non-invasive, and real-time monitoring device for detecting right-to-left shunts (RLS). Nonetheless, it has limited benefits in patients with poor temporal windows. There...
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Article
Novel data archival system for multi-omics data of human exposure to harmful substances
Exposure to harmful environmental substances influences lifelong health, but the molecular interpretation of how it affects human health is poorly understood. Therefore, a framework that can efficiently apply ...
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Open AccessInfluence of cerebral microbleeds on mechanical thrombectomy outcomes
In ischemic stroke patients undergoing endovascular treatment (EVT), we aimed to test the hypothesis that cerebral microbleeds (CMBs) are associated with clinical outcomes, while estimating the mediating effec...
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Article
The Clinical Usefulness of Targeted Temperature Management in Acute Ischemic Stroke with Malignant Trait After Endovascular Thrombectomy
Targeted temperature management (TTM) may be more beneficial after endovascular treatment (EVT) in patients with a large ischemic core. Therefore, we assessed the usefulness of TTM for such patients from a mul...
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Article
Open AccessODFM, an omics data resource from microorganisms associated with fermented foods
ODFM is a data management system that integrates comprehensive omics information for microorganisms associated with various fermented foods, additive ingredients, and seasonings (e.g. kimchi, Korean fermented ...
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Article
Open AccessPredictors and prognoses of Willisian collateral failure during mechanical thrombectomy
During mechanical thrombectomy in the anterior cerebral circulation, thrombus embolization resulting in Willisian collateral failure may lead to critical stroke outcomes due to a shutdown of leptomeningeal col...
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Article
Open AccessOptic nerve sheath diameter change in prediction of malignant cerebral edema in ischemic stroke: an observational study
In acute large anterior circulation infarct patients with large core volume, we evaluated the role of optic nerve sheath diameter (ONSD) change rates in prediction of malignant progression.
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Open AccessLocal tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study
Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT). Herein, we hypothesi...
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Article
Open AccessImmediate effects of first-line thrombectomy devices for intracranial atherosclerosis-related occlusion: stent retriever versus contact aspiration
Although stent retriever (SR) is recommended as a frontline device of endovascular treatment (EVT) for embolic large artery occlusion causing acute ischemic stroke, contact aspiration (CA) device showed simila...
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Open AccessOptimal Multiphase Computed Tomographic Angiography-based Infarct Core Estimations for Acute Ischemic Stroke
We evaluated the best methods for predicting various infarct core thresholds for endovascular treatment of ischemic stroke using parameters obtained by multiphase computed tomographic angiography (mCTA). Conse...
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Open AccessFirst draft genome sequence of the rock bream in the family Oplegnathidae
The rock bream (Oplegnathus fasciatus) is one of the most economically valuable marine fish in East Asia, and due to various environmental factors, there is substantial revenue loss in the production sector. Ther...
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Open AccessSafety and Optimal Neuroprotection of neu2000 in acute Ischemic stroke with reCanalization: study protocol for a randomized, double-blinded, placebo-controlled, phase-II trial
The potential of neuroprotective agents should be revisited in the era of endovascular thrombectomy (EVT) for acute large-artery occlusion because their preclinical effects have been optimized for ischemia and...
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Article
Open AccessImpact of varying levels of hyperglycemia on clinicoradiographic outcomes after endovascular reperfusion treatment
We evaluated the effects of admission hyperglycemia with different cut-off levels on 3-month outcomes, infarct growth, and hemorrhagic transformation in acute stroke patients with large artery occlusion of ant...
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Open AccessCentral and cerebral haemodynamic changes after antihypertensive therapy in ischaemic stroke patients: A double-blind randomised trial
Central and cerebral haemodynamic parameters can vary under similar brachial blood pressure (BP). We aimed to investigate the effects of antihypertensive agents on central and cerebral haemodynamic parameters ...
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Article
Open AccessCilostazol improves endothelial function in acute cerebral ischemia patients: a double-blind placebo controlled trial with flow-mediated dilation technique
In order to evaluate the impact of cilostazol on endothelial function, we compared the changes of flow-mediated dilation (FMD) between aspirin and cilostazol groups in patients with acute cerebral ischemia.
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Open AccessAssociation of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes
Diabetes mellitus (DM) is a risk factor for early neurological deterioration (END) in acute ischemic stroke. The prothrombotic protein fibrinogen is frequently elevated in patients with diabetes, and may be as...
