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The molecular landscape of ETMR at diagnosis and relapse

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  1. Article

    Open Access

    3D genome map** identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma

    Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A. In bo...

    Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani in Nature Communications (2023)

  2. Article

    Open Access

    Targeting fibroblast growth factor receptors to combat aggressive ependymoma

    Ependymomas (EPN) are central nervous system tumors comprising both aggressive and more benign molecular subtypes. However, therapy of the high-risk subtypes posterior fossa group A (PF-A) and supratentorial R...

    Daniela Lötsch, Dominik Kirchhofer, Bernhard Englinger, Li Jiang in Acta Neuropathologica (2021)