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Article

G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation

Biophysical analysis reveals that conserved G-rich sequences within the mRNAs of gammaherpesvirus genome maintenance proteins (GMPs) form G-quadruplexes (G4). Stabilization of mRNA G4 motifs represses GMP tran...

Pierre Murat, Jie Zhong, Lea Lekieffre, Nathan P Cowieson… in Nature Chemical Biology (2014)