7 Result(s)
within
Jean-Bernard Fiche
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open Access3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription
In mammals, insulators contribute to the regulation of loop extrusion to organize chromatin into topologically associating domains. In Drosophila the role of insulators in 3D genome organization is, however, unde...
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Article
Open AccessMulti-scale dynamic imaging reveals that cooperative motility behaviors promote efficient predation in bacteria
Many species, such as fish schools or bird flocks, rely on collective motion to forage, prey, or escape predators. Likewise, Myxococcus xanthus forages and moves collectively to prey and feed on other bacterial s...
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Article
Open AccessMultiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila
The spatial organization of chromatin at the scale of topologically associating domains (TADs) and below displays large cell-to-cell variations. Up until now, how this heterogeneity in chromatin conformation i...
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Article
Open AccessSingle-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions
At the kilo- to megabase pair scales, eukaryotic genomes are partitioned into self-interacting modules or topologically associated domains (TADs) that associate to form nuclear compartments. Here, we combine h...
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Article
Open AccessHighly efficient multicolor multifocus microscopy by optimal design of diffraction binary gratings
Multifocus microscopy (MFM) allows sensitive and fast three-dimensional imaging. It relies on the efficient design of diffraction phase gratings yielding homogeneous intensities in desired diffraction orders. ...
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Article
The mechanism of force transmission at bacterial focal adhesion complexes
Various rod-shaped bacteria mysteriously glide on surfaces in the absence of appendages such as flagella or pili. In the deltaproteobacterium Myxococcus xanthus, a putative gliding motility machinery (the Agl–Glt...
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Article
Open AccessBacterial partition complexes segregate within the volume of the nucleoid
Precise and rapid DNA segregation is required for proper inheritance of genetic material. In most bacteria and archaea, this process is assured by a broadly conserved mitotic-like apparatus in which a NTPase (...
