4 Result(s)
within
Jason Lloyd-Price
Algorithms
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Article
Open AccesssgnesR: An R package for simulating gene expression data from an underlying real gene network structure considering delay parameters
sgnesR (Stochastic Gene Network Expression Simulator in R) is an R package that provides an interface to simulate gene expression data from a given gene network using the stochastic simulation algorithm (SSA)....
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Article
Open AccessIn vivo kinetics of transcription initiation of the lar promoter in Escherichia coli. Evidence for a sequential mechanism with two rate-limiting steps
In Escherichia coli the mean and cell-to-cell diversity in RNA numbers of different genes vary widely. This is likely due to different kinetics of transcription initiation, a complex process with multiple rate-li...
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Article
Open AccessStochastic sequence-level model of coupled transcription and translation in prokaryotes
In prokaryotes, transcription and translation are dynamically coupled, as the latter starts before the former is complete. Also, from one transcript, several translation events occur in parallel. To study how ...
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Article
Open AccessInformation propagation within the Genetic Network of Saccharomyces cerevisiae
A gene network's capacity to process information, so as to bind past events to future actions, depends on its structure and logic. From previous and new microarray measurements in Saccharomyces cerevisiae followi...
