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  1. Article

    Efficacy of ampicillin against methicillin-resistant Staphylococcus aureus restored through synergy with branched poly(ethylenimine)

    β-Lactam antibiotics kill Staphylococcus aureus bacteria by inhibiting the function of cell wall penicillin-binding proteins (PBPs) 1 and 3. However, β-lactams are ineffective against PBP2a, used by methicillin-r...

    Melissa A Foxley, Anthony W Friedline, Jessica M Jensen in The Journal of Antibiotics (2016)

  2. Article

    Open Access

    Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission

    Inhibiting Plasmodium development in mosquitoes will block malaria transmission. Fibrinogen-related protein 1 (FREP1) is critical for parasite infection in Anopheles gambiae and facilitates Plasmodium invasion in...

    Guodong Niu, Bin Wang, Genwei Zhang, Jarrod B. King in Scientific Reports (2015)

  3. No Access

    Article

    Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

    Patrick Gaffney and colleagues perform a fine-map** study of the TNFAIP3 region in systemic lupus erythematosus using individuals from diverse ancestral populations. They identify a putative causal variant in a...

    Indra Adrianto, Feng Wen, Amanda Templeton, Graham Wiley, Jarrod B King in Nature Genetics (2011)