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Using Redox Potential to Detect Microbial Activities During Clavulanic Acid Biosynthesis in Streptomyces clavuligerus
Production of clavulanic acid (CA) by Streptomyces clavuligerus in a shake-flask culture increased from 92 to 180 mg l−1 with an increased O2 transfer efficiency (0.039 → 0.058 s−1), which maintained the redox po...