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  1. Article

    Open Access

    Evaluation of obesity prevention effect of black ginseng on serum, liver, and hypothalamus of mice on a high-fat diet using a metabolomics approach

    Black ginseng is being studied to prevent obesity caused by a high-fat diet (HFD). The aim of this study was to evaluate the obesity-preventing effect of black ginseng extract (BGE) in the serum, liver, and hy...

    Ye ** Kim, Dae Young Lee, Hye Rim Yang, Kyung-Hoan Im in Applied Biological Chemistry (2023)

  2. Article

    Open Access

    Wheat seedling extract and its constituents attenuate RANKL-induced differentiation and fusion of osteoclasts and bone resorption

    The occurrence of osteoporosis gradually increases within the aging population. As the side effects of therapeutic agents currently used for osteoporosis are increasing, the development of preventive and thera...

    HanGyeol Lee, Ji-Yeong Yang, Shin-Hye Kim, So-An Lim in Applied Biological Chemistry (2023)

  3. Article

    Open Access

    Improved quantification of catechin and epicatechin in red rice (Oryza sativa L.) using stable isotope dilution liquid chromatography-mass spectrometry

    Epimerization can change the catechin content and composition of samples during extraction and analytical analyses. To control the effect of epimerization, we developed a novel and stable isotope dilution liqu...

    Tae ** Kim, Ye ** Kim, Woo Duck Seo, Sang Un Park in Applied Biological Chemistry (2022)

  4. Article

    Open Access

    Improved annotation and quantification of metabolites in rice (Oryza sativa L.) seeds using two-dimensional gas chromatography–time-of-flight mass spectrometry

    Two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC  ×  GC-TOFMS) is a powerful tool for identification of compounds in complex samples. Herein, we compared the GC  ×  GC-TOFMS a...

    Seung-A. Baek, So Yeon Kim, Young ** Park, Tae ** Kim in Applied Biological Chemistry (2021)

  5. Article

    Open Access

    Metabolomic analysis reveals the interaction of primary and secondary metabolism in white, pale green, and green pak choi (Brassica rapa subsp. chinensis)

    This study aimed to comprehensively analyze primary and secondary metabolites of three different-colored (white, pale green, and green) pak choi cultivars (Brassica rapa subsp. chinensis) using gas chromatography...

    Hyeon Ji Yeo, Seung-A Baek, Ramaraj Sathasivam in Applied Biological Chemistry (2021)

  6. Article

    Open Access

    Gene flow from transgenic soybean, developed to obtain recombinant proteins for use in the skin care industry, to non-transgenic soybean

    Soybean has been recognized as a useful platform for heterologous protein production. This study compared the pollen characteristics of transgenic and non-transgenic soybean and investigated the rate of gene f...

    Do Young Kim, Min Sik Eom, Hye ** Kim, Eun Mi Ko in Applied Biological Chemistry (2020)

  7. Article

    Open Access

    Influence of light-emitting diodes on phenylpropanoid biosynthetic gene expression and phenylpropanoid accumulation in Agastache rugosa

    Agsatache rugosa (Korean mint), belongs to the mint family and it has various medicinal properties. In addition, it has several valuable compounds such as monoterpenes and phenylpropanoid compounds. Amongst these...

    Woo Tae Park, Sun Kyung Yeo, Ramaraj Sathasivam in Applied Biological Chemistry (2020)

  8. Article

    Open Access

    Metabolic profiling reveals glucose and fructose accumulation in gcr1 knock-out mutant of Arabidopsis

    The ligands and functions of GCR1, the putative G-protein coupled receptor gene of Arabidopsis thaliana, and its role in metabolism are not well studied. Herein, we determined the contents of different pigments, ...

    Seung-A Baek, Soon Kil Ahn, Kil Won Kim, Jaehyuk Choi in Applied Biological Chemistry (2019)

  9. No Access

    Article

    Determination and quantification of arbutin in plants using stable isotope dilution liquid chromatography–mass spectrometry

    Arbutin is a very safe whitening agent for human skin. Since it is more expensive than other agents and has a challenging synthesis, novel methods to obtain this valuable agent are needed. In this study, we d...

    Tae ** Kim, Young ** Park, Sang Un Park, Sun-Hwa Ha in Applied Biological Chemistry (2018)

  10. Article

    Correction to: Metabolic profiling of pale green and purple kohlrabi (Brassica oleracea var. gongylodes)

    Unfortunately, in the online published article, the second author’s given name was wrongly published. The correct given name should be “Hyeon Ji”.

    Chang Ha Park, Hyeon Ji Yeo, Nam Su Kim, Ye Eun Park in Applied Biological Chemistry (2018)

  11. No Access

    Article

    Phytochemical profiles of Brassicaceae vegetables and their multivariate characterization using chemometrics

    Twenty-eight metabolites were extracted from nine Brassicaceae of Korean origin (broccoli, Brussels sprouts, cabbage, Chinese cabbage, kale, kohlrabi, pak choi, radish sprouts, and red cabbage) and analyzed us...

    Kyoung Bok Lee, Ye ** Kim, Hyo ** Kim, Jaehyuk Choi in Applied Biological Chemistry (2018)

  12. No Access

    Article

    Expression levels of carotenoid biosynthetic genes and carotenoid production in the callus of scutellaria baicalensis exposed to white, blue, and red light-emitting diodes

    In the present study, efforts were made to determine effect of different light wavelengths on carotenoid biosynthesis in Scutellaria baicalensis, a promising traditional herbal medicine used in North America and ...

    Pham Anh Tuan, Chang Ha Park, Woo Tae Park, Yeon Bok Kim in Applied Biological Chemistry (2017)

  13. No Access

    Article

    Metabolic profiling of pale green and purple kohlrabi (Brassica oleracea var. gongylodes)

    Kohlrabi (Brassica oleracea var. gongylodes) is a dietary Brassica vegetable with noted health-beneficial properties associated with its numerous metabolites. The aim of this study was to elucidate phenotypic var...

    Chang Ha Park, Hyun Ji Yeo, Nam Su Kim, Park Ye Eun in Applied Biological Chemistry (2017)

  14. No Access

    Article

    Targeted metabolite profiling to evaluate unintended metabolic changes of genetic modification in resveratrol-enriched rice (Oryza sativa L.)

    Resveratrol-enriched rice (RR) includes the stilbene synthase gene for resveratrol synthesis and the phosphinothricin-N-acetyltransferase gene for glufosinate tolerance. To investigate unintended effects resultin...

    Min Sung Kim, So-Hyeon Baek, Sang Un Park, Kyung-Hoan Im in Applied Biological Chemistry (2017)

  15. No Access

    Article

    Metabolomics of differently colored Gladiolus cultivars

    Gladiolus (Gladiolus grandiflora Hort.) plants are a perennial favorite, known for their beautiful flowers of many different colors. In this study, we determined metabolic differences between seven Gladiolus cult...

    Yeon Bok Kim, Soo-Yun Park, Chang Ha Park, Woo Tae Park in Applied Biological Chemistry (2016)

  16. No Access

    Article

    Determination of lipophilic metabolites for species discrimination and quality assessment of nine leafy vegetables

    The lipophilic compounds in nine vegetables consumed in Korea were characterized for diversity in phytochemical content. We also analyzed the relationships among these compounds in terms of their contents. The...

    Tae ** Kim, Kyoung Bok Lee, Seung-A Baek in Journal of the Korean Society for Applied … (2015)

  17. No Access

    Article

    Identification and quantification of carotenoids in paprika fruits and cabbage, kale, and lettuce leaves

    Twelve carotenoids were identified in Korean leafy vegetables and paprikas. by high-performance liquid chromatography, Carotenoid contents varied greatly, with red paprika having a higher antheraxanthin and ca...

    Soo-Yun Park, Su Ryun Choi, Sun-Hyung Lim in Journal of the Korean Society for Applied … (2014)

  18. No Access

    Article

    Molecular cloning and characterization of mevalonic acid (MVA) pathway genes and triterpene accumulation in Panax ginseng

    Panax ginseng Meyer is one of the most important medicinal plants in Asia, and ginseng has attracted considerable attention worldwide. Triterpene saponins (ginsenosides) are the main bioactive co...

    Yong-Kyoung Kim, Yeon Bok Kim, Jae Kwang Kim in Journal of the Korean Society for Applied … (2014)

  19. No Access

    Article

    Determination of indole-3-carbinol and indole-3-acetonitrile in Brassica vegetables using high-performance liquid chromatography with fluorescence detection

    A simple and sensitive method for determining indole-3-carbinol (I3C) and indole-3-acetonitrile (I3A) from Brassica vegetable was developed using high-performance liquid chromatography with fluorescence detection...

    Si Young Lee, Sang Mi Chu, Si Myung Lee in Journal of the Korean Society for Applied … (2010)

  20. No Access

    Article

    Metabolic Fingerprinting Study on the Substantial Equivalence of Genetically Modified (GM) Chinese Cabbage to Non-GM Cabbage

    Genetically modified (GM) Chinese cabbage containing the bar gene was compared to 24 non-GM Chinese cabbage varieties to evaluate unwanted changes in GM crops using HPLC-DAD-based metabolic fingerprinting to char...

    Jae Kwang Kim, Tae Hun Ryu, Soo In Sohn in Journal of the Korean Society for Applied … (2009)