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    Article

    Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function

    Hypoxia-inducible factor (HIF)-1α is a master regulator of inflammatory activities of myeloid cells, including neutrophils and macrophages. These studies examine the role of myeloid cell HIF-1α in regulating a...

    Laura E. Crotty Alexander, Kathryn Akong-Moore in Journal of Molecular Medicine (2013)

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    Open Access

    Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9

    As genetically engineered mutant mice deficient in single genes are usually generated on a C57BL/6 background, to study mast cell trafficking in mutant mice, we initially investigated whether mast cells accumu...

    Suzan Pae, Jae Youn Cho, Shanna Dayan, Marina Miller, Alan D. Pemberton in Immunogenetics (2010)