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    Article

    The application of repeated testing and monoexponential regressions to classify individual cardiorespiratory fitness responses to exercise training

    We tested the hypothesis that monoexponential regressions will increase the certainty in response estimates and confidence in classification of cardiorespiratory fitness (CRF) responses compared to a recently ...

    Jacob T. Bonafiglia, Robert Ross, Brendon J. Gurd in European Journal of Applied Physiology (2019)

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    Article

    The impact of acute and chronic exercise on Nrf2 expression in relation to markers of mitochondrial biogenesis in human skeletal muscle

    To examine the relationship between changes in nuclear factor erythroid 2-related factor 2 (Nrf2) expression and markers of mitochondrial biogenesis in acutely and chronically exercised human skeletal muscle.

    Hashim Islam, Jacob T. Bonafiglia in European Journal of Applied Physiology (2020)

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    Article

    Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle

    Fasting rapidly (≤ 6 h) activates mitochondrial biogenic pathways in rodent muscle, an effect that is absent in human muscle following prolonged (10–72 h) fasting. We tested the hypotheses that fasting-induced...

    Hashim Islam, Alessandra Amato in Pflügers Archiv - European Journal of Phys… (2021)

  4. Article

    Open Access

    Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study

    Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is conside...

    Camilla J. Williams, Zhixiu Li, Nicholas Harvey in Journal of Biomedical Science (2021)

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    Article

    Exploring Differences in Cardiorespiratory Fitness Response Rates Across Varying Doses of Exercise Training: A Retrospective Analysis of Eight Randomized Controlled Trials

    This study tested the hypothesis that greater mean changes in cardiorespiratory fitness (CRF), in either the absence or presence of reduced interindividual variability, explain larger CRF response rates follow...

    Jacob T. Bonafiglia, Nicholas Preobrazenski, Hashim Islam in Sports Medicine (2021)

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    Article

    Interindividual Differences in Trainability and Moderators of Cardiorespiratory Fitness, Waist Circumference, and Body Mass Responses: A Large-Scale Individual Participant Data Meta-analysis

    Although many studies have assumed variability reflects variance caused by exercise training, few studies have examined whether interindividual differences in trainability are present following exercise traini...

    Jacob T. Bonafiglia, Paul A. Swinton, Robert Ross, Neil M. Johannsen in Sports Medicine (2022)

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    Article

    No acute hyperglycemia induced impairment in brachial artery flow-mediated dilation before or after aerobic exercise training in young recreationally active males

    There is some evidence that transient endothelial dysfunction induced by acute hyperglycemia may be attenuated by a single bout of aerobic exercise. However, the impact of aerobic exercise training on acute hy...

    Jennifer S. Williams, Jacob T. Bonafiglia in European Journal of Applied Physiology (2023)