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  1. No Access

    Article

    Identification of the cyclin D1b mRNA variant in mouse

    Cyclin D1 plays a key regulatory role during the G1 phase of the cell cycle and its gene is amplified and over-expressed in many cancers. The cyclin D1b mRNA variant was established in human cells and recent f...

    Jack Wu, Si-hung Wu, Aliccia Bollig, Archana Thakur… in Molecular Biology Reports (2009)

  2. No Access

    Article

    Expression profile of microRNAs in c-Myc induced mouse mammary tumors

    c-Myc is a transcription factor overexpression of which induces mammary cancer in transgenic mice. To explore whether certain microRNAs (mirRNA) mediate c-Myc induced mammary carcinogenesis, we studied mirRNA ...

    Yuan Sun, Jack Wu, Si-hung Wu, Archana Thakur… in Breast Cancer Research and Treatment (2009)

  3. Article

    Open Access

    An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals

    MI-319 is a synthetic small molecule designed to target the MDM2-P53 interaction. It is closely related to MDM2 antagonists MI-219 and Nutlin-3 in terms of the expected working mechanisms. The purpose of this ...

    Ramzi M Mohammad, Jack Wu, Asfar S Azmi, Amro Aboukameel, Angela Sosin… in Molecular Cancer (2009)

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  4. No Access

    Article

    Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation

    Transcription of a pre-mRNA in eukaryotic cells elongates from the 5′ to the 3′ end, but intron removal during a pre-mRNA splicing does not always proceed in this orientation. In this study, we identified eigh...

    Min Yang, Jack Wu, Si-hung Wu, An-ding Bi, D. Joshua Liao in Molecular Biology Reports (2012)

  5. Article

    Open Access

    Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal Transition

    Here we demonstrate for the first time that targeted inhibition of nuclear exporter protein exportin 1 (XPO1) also known as chromosome maintenance region 1 (CRM1) by Selective Inhibitor of Nuclear Export (SINE...

    Asfar S. Azmi, Irfana Muqbil, Jack Wu, Amro Aboukameel… in Scientific Reports (2015)

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  6. No Access

    Reference Work Entry In depth

    Knowledge Management and Sustainable Development

    Jack Wu, Man Fung Lo, Artie W. Ng in Encyclopedia of Sustainability in Higher Education (2019)

  7. No Access

    Living Reference Work Entry In depth

    Knowledge Management and Sustainable Development

    Jack Wu, Man Fung Lo, Artie W. Ng in Encyclopedia of Sustainability in Higher Education