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Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation
Transcription of a pre-mRNA in eukaryotic cells elongates from the 5′ to the 3′ end, but intron removal during a pre-mRNA splicing does not always proceed in this orientation. In this study, we identified eigh...
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Article
Identification of the cyclin D1b mRNA variant in mouse
Cyclin D1 plays a key regulatory role during the G1 phase of the cell cycle and its gene is amplified and over-expressed in many cancers. The cyclin D1b mRNA variant was established in human cells and recent f...