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Open AccessClinico-biological significance of suppressor of cytokine signaling 1 expression in acute myeloid leukemia
Suppressor of cytokine signaling 1 (SOCS1) protein, which encodes a member of signal transducers and activators of transcription-induced inhibitors, takes part in a negative regulation of cytokine signaling. T...
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Article
Open AccessIdeal cardiovascular health status and its association with socioeconomic factors in Chinese adults in Shandong, China
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. In 2010, a goal released by the American Heart Association (AHA) Committee focused on the primary reduction in cardiov...
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Article
Open AccessTP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution
The TP53 mutation is frequently detected in acute myeloid leukemia (AML) patients with complex karyotype (CK), but the stability of this mutation during the clinical course remains unclear. In this study, TP53 mu...
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Article
Open AccessDynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome
Recently, mutations of the additional sex comb-like 1 (ASXL1) gene were identified in patients with myelodysplastic syndrome (MDS), but the interaction of this mutation with other genetic alterations and its dyna...
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Article
Open AccessDistinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia
Aberrant activation of Wnt signalling through hypermethylation of Wnt inhibitor genes is involved in several human malignancies, including acute myeloid leukaemia (AML). It remains unclear whether hypermethyla...
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Article
Open AccessHigh bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes
Angiogenic factors have an essential role in normal and pathologic angiogenesis. However, the clinical implication of angiogenic factor expression in myelodysplastic syndromes (MDS) remains unclear.
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Article
Open AccessHigh tunabilty Ba0.6Sr0.4TiO3 thin films fabricated on Pt–Si substrates with La0.5Sr0.5CoO3 buffer layer
Ba0.6Sr0.4TiO3 (BST) thin films for the tunable microwave devices were grown using pulsed laser deposition (PLD) on Pt/Ti/SiO2/Si (Pt–Si) substrates with La0.5Sr0.5CoO3 (LSCO) buffer layers. For comparison, the f...
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Article
Erratum: A novel fluorescence-based multiplex PCR assay for rapid simultaneous detection of CEBPA mutations and NPM mutations in patients with acute myeloid leukemias
Correction to: Leukemia (2007) 20, 1899–1903. doi:10.1038/sj.leu.2404331 Since the publication of the above paper, the authors have noticed an error in the sequence of primers used for TAD1, TAD2 and bZIP ampl...
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Article
Epidemiological characteristics of diabetes mellitus and impaired glucose regulation in a Chinese adult population: the Shanghai Diabetes Studies, a cross-sectional 3-year follow-up study in Shanghai urban communities
To estimate the prevalence and incidence of diabetes mellitus and impaired glucose regulation (IGR) in a Chinese population aged 20–94 years.
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Erratum to: Building a mouse model hallmarking the congenital human cytomegalovirus infection in central nervous system