25,546 Result(s)
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J. W. **an
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Open AccessImpact of symptom duration and mechanical circulatory support on prognosis in cardiogenic shock complicating acute myocardial infarction
Mortality rates in patients with cardiogenic shock complicating acute myocardial infarction (AMICS) remain high despite advancements in AMI care. Our study aimed to investigate the impact of prehospital sympto...
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Correction: Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65
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Open AccessSleep profiles of different psychiatric traits
Disturbed sleep comes in many forms. While the key role of sleep in mental health is undisputed, our understanding of the type of slee** problems that manifest in the early stages of psychiatric disorders is...
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Open AccessSearch for the \( {B}_s^0 \) → μ+μ−γ decay
A search for the fully reconstructed B s 0 ...
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Open AccessDigital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art
Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in Parkinson’s disease (PD), by allowing objective and recurrent mea...
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Open AccessMeasurement of e+e− → ωη′ cross sections at \( \sqrt{s} \) = 2.000 to 3.080 GeV
We measured the Born cross sections for the process e+e− → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statis...
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Health-related quality of life and symptoms of chronic myeloid leukemia patients after discontinuation of tyrosine kinase inhibitors: results from the EURO-SKI Trial
Limited data is available on the health-related quality of life (HRQoL) and symptoms of patients with chronic myeloid leukemia (CML) who are in treatment-free remission (TFR). We herein report HRQoL results fr...
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Open AccessExploring long-term retention and reactivation of micropollutant biodegradation capacity
The factors limiting micropollutant biodegradation in the environment and how to stimulate this process have often been investigated. However, little information is available on the capacity of microbial commu...
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Open AccessModification of the Metallic Magnetic Calorimeter Fabrication Process for High Production Yield
We have modified the fabrication processes of metallic magnetic calorimeters (MMCs) to improve production yield. Key modifications include (i) the stress mitigation of the sputtered Nb film by optimizing the A...
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Turing instability and pattern formation induced by noise in the modified SIR model
In the process of the spread of infectious diseases, it is often affected by demographic noise and stochastic disturbance. But the relationship between the noise and the dynamical mechanism is always in a stat...
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Open AccessModulation of the Meisenheimer complex metabolism of nitro-benzothiazinones by targeted C-6 substitution
Tuberculosis, caused by Mycobacterium tuberculosis, remains a major public health concern, demanding new antibiotics with innovative therapeutic principles due to the emergence of resistant strains. Benzothiazino...
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Open AccessCorrection: Recurrent disease detection after resection of pancreatic ductal adenocarcinoma using a recurrence-focused surveillance strategy (RADAR-PANC): protocol of an international randomized controlled trial according to the Trials within Cohorts design
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Open AccessTraining and assessing convolutional neural network performance in automatic vascular segmentation using Ga-68 DOTATATE PET/CT
To evaluate a convolutional neural network’s performance (nnU-Net) in the assessment of vascular contours, calcification and PET tracer activity using Ga-68 DOTATATE PET/CT. Patients who underwent Ga-68 DOTATA...
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Open AccessRobotic hepaticojejunostomy training in novices using robotic simulation and dry-lab suturing (ROSIM): randomized controlled crossover trial
Robotic suturing training is in increasing demand and can be done using suture-pads or robotic simulation training. Robotic simulation is less cumbersome, whereas a robotic suture-pad approach could be more ef...
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Open AccessInsights into In Situ Benthic Caging Tests for Ecotoxicity Assessments Targeting Discharging Groundwater Contaminant Plumes
While in situ toxicity testing with caged organisms has been used to assess surface water and sediment contamination, no successful application to benthic organisms exposed to highly contaminated groundwater p...
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The verification of the utility of a commercially available phantom combination for quality control in contrast-enhanced mammography
Contrast-enhanced mammography is being increasingly implemented clinically, providing much improved contrast between tumour and background structures, particularly in dense breasts. Although CEM is similar to ...
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Author Correction: Restoration of vision after transplantation of photoreceptors
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Open AccessAsciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results
Asciminib targets the BCR::ABL1 myristoyl pocket, maintaining activity against BCR::ABL1T315I, which is resistant to most approved adenosine triphosphate–competitive tyrosine kinase inhibitors. We report updated ...
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Transient dynamics of polymer emulsification inside a twin-screw extruder: effect on process stability and particle size distribution
Solvent-free extrusion emulsification (SFEE) is a recently developed process for producing submicron particles of high viscosity polymers using a twin-screw extruder without hazardous solvents. Its rate depend...
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Open AccessInterdisciplinary assessment and treatment of paediatric drooling: two decades of experience by the Nijmegen saliva control team reflected in a stepwise algorithm
Anterior and posterior drooling are prevalent comorbidities in children with neurodevelopmental disabilities. Considering the heterogeneity of the patient population and the multifactorial aetiology of droolin...
