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Open AccessAssociation between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population
To examine the cross-sectional association between baseline depressive symptoms and the presence of type 2 diabetes (T2D), and its association with glycated hemoglobin (HbA1c) and other metabolic variables, an...
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Article
Intensive Weight-Loss Lifestyle Intervention Using Mediterranean Diet and COVID-19 Risk in Older Adults: Secondary Analysis of PREDIMED-Plus Trial
We tested the effects of a weight-loss intervention encouraging energy-reduced MedDiet and physical activity (PA) in comparison to ad libitum MedDiet on COVID-19 incidence in older adults.
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Analysis of the evolution of cortical and trabecular bone compartments in the proximal femur after spinal cord injury by 3D-DXA
Marked trabecular and cortical bone loss was observed at the proximal femur short-term after spinal cord injury (SCI). 3D-DXA provided measurement of vBMD evolution at both femoral compartments and cortical th...
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Article
Effect of recent spinal cord injury on the OPG/RANKL system and its relationship with bone loss and the response to denosumab therapy
There is marked bone loss after spinal cord injury (SCI); however, its pathogenesis and clinical management remain unclear. The increased circulating levels of receptor activator of nuclear factor kB ligand (R...
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Article
Evening chronotype associates with obesity in severely obese subjects: interaction with CLOCK 3111T/C
Chronotype has been related to obesity and metabolic disturbances. However, little is known about the relationship between circadian preferences and genetic background in CLOCK genes with obesity and weight loss ...
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Article
Clinical onset of celiac disease after duodenal switch: a case report
To our knowledge, this is the first reported case of clinical onset of celiac disease (CD) following duodenal switch surgery. A 61-year-old obese woman developed severe diarrhea soon after bariatric surgery (B...
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Article
Open AccessLEADER 5: prevalence and cardiometabolic impact of obesity in cardiovascular high-risk patients with type 2 diabetes mellitus: baseline global data from the LEADER trial
Epidemiological data on obesity are needed, particularly in patients with type 2 diabetes mellitus (T2DM) and high cardiovascular (CV) risk. We used the baseline data of liraglutide effect and action in diabet...
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Article
Denosumab increases sublesional bone mass in osteoporotic individuals with recent spinal cord injury
Osteoporosis is a frequent complication related to spinal cord injury (SCI), and data on osteoporosis treatment after SCI is scarce. Treatment with denosumab increases lumbar and femoral BMD and decreases bone...
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Article
Risk factors for the development of osteoporosis after spinal cord injury. A 12-month follow-up study
Spinal cord injury (SCI) has been associated with a marked bone loss after injury and a consequent increased risk of osteoporosis. The evaluation of bone mineral density shortly after SCI is a simple and effec...
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Article
Endothelial Function in Hypertensive Obese Patients: 1 year After Surgically Induced Weight Loss
The aim of this study was to describe the effect of surgically induced weight loss on vascular function measured by flow-mediated dilatation (FMD) in hypertensive obese patients. This prospective study include...
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Article
Prognostic significance of circulating tumor cells in advanced non-small cell lung cancer patients treated with docetaxel and gemcitabine
To evaluate the association in the change of circulating tumor cell (CTC) levels and clinical outcomes (PFS and OS) in patients with advanced non-small cell lung cancer (NSCLC) treated homogenously with doceta...
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Spinal cord toxoplasmosis
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Article
fMRI of the sensorimotor cortex in patients with traumatic brain injury after intensive rehabilitation
For evaluating the patterns of brain activation in sensorimotor areas following motor rehabilitation, seven male patients diagnosed with TBI underwent an fMRI study before and after being subjected to motor re...
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Article
Open AccessPrevalence and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage on admission to different hospital sectors in two European countries
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Article
Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets
Islet transplantation is a potential cure for diabetes; however, rates of graft failure remain high. The aim of the present study was to determine whether amyloid deposition is associated with reduced beta cel...
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Article
Type 2 Diabetes Mellitus and the Metabolic Syndrome Following Sleeve Gastrectomy in Severely Obese Subjects
Data on the effectiveness of sleeve gastrectomy in improving or resolving type 2 diabetes mellitus (T2DM) and the metabolic syndrome (MS) are scarce.
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Article
Phenotype changes at the onset of type 1 diabetes in young adults from a Mediterranean area throughout the last decade
The Accelerator hypothesis postulates that Type 1 Diabetes (T1D) and Type 2 Diabetes are mostly the same disorder. Till now, the data testing the hypothesis and the importance of BMI and insulin resistance in ...
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Critical assessment of the current guidelines for the management and treatment of morbidly obese patients
An interdisciplinary panel of specialists met in Mallorca in the first European Symposium on Morbid Obesity entitled; “Morbid Obesity, an Interdisciplinary Approach”. During the two and half days of the meetin...
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The importance of diagnostic criteria in the association between the metabolic syndrome and cardiovascular disease in obese subjects
To investigate whether the association between the metabolic syndrome (MS) and cardiovascular disease (CVD) in obese adults is influenced by the criteria used to diagnose the MS.
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The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice
Abstract