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Article
Preserved incretin effect in type 1 diabetic patients with end-stage nephropathy treated by combined heterotopic pancreas and kidney transplantation
Insulin secretion is stimulated better by oral than by intravenous glucose (incretin effect). The contribution of the autonomic nervous system to the incretin effect after oral glucose in humans is unclear. We...
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Article
Basal and nutrient-stimulated pancreatic and gastrointestinal hormone concentrations in type-l-diabetic patients after successful combined pancreas and kidney transplantation
The secretion of pancreatic and gastrointestinal hormones in the basal state and after nutrient stimuli (50 g glucose, 50 g protein, or 30 g triglyceride administered on separate occasions) was assessed in ten...
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Article
Consequences of systemic venous drainage and denervation of heterotopic pancreatic transplants for insulin/C-peptide profiles in the basal state and after oral glucose
Plasma glucose, immunoreactive insulin and C-peptide concentrations were compared in nine pancreas-kidney-transplanted patients (systemic venous drainage) and in ten non-diabetic kidney-transplanted patients w...
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Article
Complications of plasma exchange in patients with neurological diseases
Plasma exchange has proven to be effective in diseases of established or presumed autoimmune etiology as well as in hyperviscosity syndromes and some rare metabolic disorders. Its application is thought to be ...
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Chapter and Conference Paper
Plasma concentrations of atrial natriuretic peptide (α- h-ANP 1–28) during exercise and relationship to hemodynamic parameters in man
To elucidate the diagnostic value of Atrial Natriuretic Peptide (ANP), ANP plasma concentrations were determined by radioimmunoassay in 15 patients with coronary or valvular heart diseases who were to undergo ...
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Chapter and Conference Paper
Atrial natriuretic peptide (Alpha- h -ANP) in 157 children with congenital heart disease
Atrial natriuretic peptide plasma concentrations were determined in a group of 157 children with congenital heart diseases undergoing cardiac catheterisation. Valvular heart diseases associated with typical at...
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Chapter and Conference Paper
Atrial Natriuretic Peptide as a Humoral Marker in 157 Children with Congenital Heart Diseases
Distension of the atria seems to be the principal stimulus for ANP secretion from myoendocrine cells [1, 7, 9, 10]. In congestive heart failure (CHF) and volume overload atrial distension is caused by an incre...
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Article
Binding sites of atrial natriuretic peptide in human renal tissue — Quantification by in vitro receptor autoradiography
Specific binding sites for atrial natriuretic peptide (99–126) in different areas of normal human renal tissue were quantified by in vitro autoradiography. Our data represent the first characterization of ANP ...
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Article
Isolation and structural analysis of the circulating human cardiodilatin (alpha ANP)
A new method was applied to isolate a polypeptide hormone from human blood. The polypeptides from 1,000 1 of hemofiltrate with a molecular weight lower than 20 kDaltons were adsorbed to 2.5 kg alginic acid, th...