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  1. No Access

    Article

    Modulation of in utero total body irradiation induced newborn mouse growth retardation by maternal manganese superoxide dismutase-plasmid liposome (MnSOD-PL) gene therapy

    To determine the effects of manganese superoxide dismutase (MnSOD) plasmid liposome (PL) maternal radioprotection on fetal mice, timed pregnant female mice (E14 gestation) were irradiated to 3.0 Gy total body ...

    M W Epperly, T Smith, X Zhang, J P Goff, D Franicola, B Greenberger… in Gene Therapy (2011)

  2. No Access

    Article

    Intraesophageal MnSOD-plasmid liposome enhances engraftment and self-renewal of bone marrow derived progenitors of esophageal squamous epithelium

    We evaluated whether the improved esophageal radiation tolerance following Manganese Superoxide Dismutase (MnSOD)-Plasmid Liposomes was explained by improved engraftment of bone marrow-derived progenitors. C57...

    Y Niu, M W Epperly, H Shen, T Smith, H Wang, J S Greenberger in Gene Therapy (2008)

  3. No Access

    Article

    Gene therapy approaches for stem cell protection

    Cytotoxic exposure of bone marrow and other non-hematopoietic organs containing self-renewing stem cell populations is associated with damage to the supportive microenvironment. Recent evidence indicates that ...

    J S Greenberger in Gene Therapy (2008)

  4. No Access

    Article

    Inhalation delivery of manganese superoxide dismutase-plasmid/liposomes protects the murine lung from irradiation damage

    Intratracheal injection of manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) complexes has been demonstrated to delay the onset and reduce the extent of ionizing irradiation-induced murine pulmonary o...

    M Carpenter, M W Epperly, A Agarwal, S Nie, L Hricisak, Y Niu… in Gene Therapy (2005)

  5. No Access

    Article

    Cell phenotype specific kinetics of expression of intratracheally injected manganese superoxide dismutase–plasmid/liposomes (MnSOD–PL) during lung radioprotective gene therapy

    Intratracheal (IT) injection of manganese superoxide dismutase–plasmid/liposome (MnSOD-PL) complexes prior to whole lung irradiation of C57BL/6J mice provides significant protection from acute and chronic irra...

    M W Epperly, H L Guo, M Jefferson, S Nie, J Gretton, M Bernarding… in Gene Therapy (2003)

  6. Article

    Gene therapy for radiation protection

    J S Greenberger in Gene Therapy (1999)

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