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    Enzymatic production of single-stranded DNA as a target for fluorescence in situ hybridization

    This study demonstrates that Exonuclease III (Exo III) can be used to produce sufficient single-stranded (ss)DNA in chromosomes and cells to allow in situ hybridization. In this study, all of the probes were m...

    H. van Dekken, D. Pinkel, J. Mullikin, J. W. Gray in Chromosoma (1988)