9 Result(s)

Article

Pancreatic islet and progenitor cell surface markers with cell sorting potential

The aim of the study was to identify surface bio-markers and corresponding antibody tools that can be used for the imaging and immunoisolation of the pancreatic beta cell and its progenitors. This may prove es...

J. Hald, T. Galbo, C. Rescan, L. Radzikowski, A. E. Sprinkel, H. Heimberg… in Diabetologia (2012)

Article

Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat

Use of the second-generation antipsychotic drugs (SGAs) results in the development of obesity and a type 2 diabetes-like syndrome. We hypothesised that, in addition to the insulin resistance associated with th...

G. C. Smith, C. Chaussade, M. Vickers, J. Jensen, P. R. Shepherd in Diabetologia (2008)

Article

Global gene expression profiling and histochemical analysis of the develo** human fetal pancreas

An immunohistochemical and genomic analysis of human pancreatic development from 9–23 weeks of fetal age was undertaken to provide a comparative analysis of human and murine islet development.

S. A. Sarkar, S. Kobberup, R. Wong, A. D. Lopez, N. Quayum, T. Still… in Diabetologia (2008)

Article

Global myocardial perfusion and diastolic function are impaired to a similar extent in patients with type 2 diabetes mellitus and in patients with coronary artery disease—evaluation by contrast echocardiography and pulsed tissue Doppler

Using modern echocardiography, we quantified the extent of global myocardial function and perfusion abnormalities in patients with type 2 diabetes and compared this with the hypothetically similar extent of im...

V. Dounis, T. Siegmund, A. Hansen, J. Jensen, P.-M. Schumm-Draeger… in Diabetologia (2006)

Article

Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure

Hypertrophic and failing hearts have increased utilisation of glucose, but also develop insulin resistance and reduced ability to produce ATP. Increased levels of the IL-6-related cytokine leukaemia inhibitory...

G. Florholmen, G. H. Thoresen, A. C. Rustan, J. Jensen, G. Christensen… in Diabetologia (2006)

Article

Glucocorticoid-induced insulin resistance in skeletal muscles: defects in insulin signalling and the effects of a selective glycogen synthase kinase-3 inhibitor

Treatment with glucocorticoids, especially at high doses, induces insulin resistance. The aims of the present study were to identify the potential defects in insulin signalling that contribute to dexamethasone...

J. Ruzzin, A. S. Wagman, J. Jensen in Diabetologia (2005)

Article

40^th EASD Annual Meeting of the European Association for the Study of Diabetes

M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)

Article

Chronic hyperglycaemia promotes lipogenesis and triacylglycerol accumulation in human skeletal muscle cells

The present study was conducted to evaluate the effect of hyperglycaemia in itself on glucose and lipid metabolism in human skeletal muscle cells.

V. Aas, E. T. Kase, R. Solberg, J. Jensen, A. C. Rustan in Diabetologia (2004)

Article

35th Annual Meeting of the European Association for the Study of Diabetes

A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)