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Truncated RUNX1 protein generated by a novel t(1;21)(p32;q22) chromosomal translocation impairs the proliferation and differentiation of human hematopoietic progenitors

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    Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy

    In most clinical trials, human mesenchymal stem cells (hMSCs) are expanded in vitro before implantation. The genetic stability of human stem cells is critical for their clinical use. However, the relationship bet...

    J C Estrada, Y Torres, A Benguría, A Dopazo, E Roche… in Cell Death & Disease (2013)

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