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  1. No Access

    Article

    Enrollment of older metastatic breast cancer patients in first-line clinical trials: 9-year experience of the large-scale real-life multicenter French ESME cohort

    Older cancer patients are underrepresented in clinical trials. We aimed to evaluate the enrollment of older women aged 70 years old (yo) or over with metastatic breast cancer (MBC) in clinical trials.

    M. Bringuier, M. Carton, C. Levy, A. Patsouris… in Breast Cancer Research and Treatment (2022)

  2. No Access

    Article

    Characteristics of IDH-mutant gliomas with non-canonical IDH mutation

    Approximately 10% of IDH-mutant gliomas harbour non-canonical IDH mutations (non-p.R132H IDH1 and IDH2 mutations).

    L. Poetsch, C. Bronnimann, H. Loiseau, J. S. Frénel… in Journal of Neuro-Oncology (2021)

  3. No Access

    Chapter

    Gynecological Carcinosarcomas

  4. Carcinosarcomas (also known as malignant mixed müllerian tumors) are rare and highly aggressive epithelial malignancies that contain both malignant sarcomatous a...

    5. D. Berton-Rigaud, J. S. Frenel, M. Devouassoux-Shisheboran… in Ovarian Cancers (2017)

  5. No Access

    Article

    Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience

    IDH1/2 mutations and 1p/19q codeletion occur frequently in anaplastic gliomas and are prognostic factors. We combined these two biomarkers to stratify patients treated for anaplastic oligodendroglioma (AO). 43...

    J. S. Frenel, C. Leux, D. Loussouarn, A.-G. Le Loupp… in Journal of Neuro-Oncology (2013)

  6. No Access

    Chapter

    Mécanismes de résistance à la chimiothérapie

    Le développement de mécanisme de résistance par la tumeur est un obstacle majeur de l’efficacité à la chimiothérapie. Ces mécanismes sont complexes et multifactoriels. Ils sont le reflet du polymorphisme de la...

    M. Campone, E. Bourbouloux, D. Berton-Rigaud, A. Le Pourhiet… in Cancer du sein avancé (2007)