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  1. No Access

    Article

    Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway

    Salmonella have been demonstrated to inhibit tumor growth. However, the mechanism of Salmonella-induced tumor cell death is less defined. Autophagy is a cellular process that mediates the degradation of long-live...

    C-H Lee, S-T Lin, J-J Liu, W-W Chang, J-L Hsieh, W-K Wang in Gene Therapy (2014)

  2. Article

    Open Access

    One-carbon metabolism factors and endometrial cancer risk

    This is the largest prospective cohort analysis to assess how dietary factors involved in one-carbon metabolism are associated with endometrial cancer incidence, using 26 years of follow-up data from the Nurse...

    J J Liu, A Hazra, E Giovannucci, S E Hankinson, B Rosner… in British Journal of Cancer (2013)

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  3. No Access

    Article

    Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis

    It has been shown that interleukin 18 (IL-18) exerts antitumor activity. In this study, we investigated whether oncolytic adenovirus-mediated gene transfer of IL-18 could induce strong antitumor activity. A tumor...

    J-N Zheng, D-S Pei, L-J Mao, X-Y Liu, F-H Sun, B-F Zhang, Y-Q Liu… in Cancer Gene Therapy (2010)

  4. No Access

    Article

    The LRRK2 Gly2385Arg variant is associated with Parkinson’s disease: genetic and functional evidence

    Evidence of LRRK2 haplotypes associated with Parkinson’s disease (PD) risk was recently found in the Chinese population from Singapore, and a common LRRK2 missense variant, Gly2385Arg, was independently detect...

    E. K. Tan, Y. Zhao, L. Skipper, M. G. Tan, A. Di Fonzo, L. Sun… in Human Genetics (2007)

  5. No Access

    Article

    Quercetin inhibits LPS-induced delay in spontaneous apoptosis and activation of neutrophils

    Objective: To investigate the effects of quercetin, an herbal flavonoid, on LPS-induced delay in spontaneous apoptosis, adhesion molecules (CD62L, CD11b/CD18) expression of neutrophils, a...

    J.-J. Liu, C.-W. Song, Y. Yue, C.-G. Duan, J. Yang, T. He… in Inflammation Research (2005)

  6. No Access

    Article

    Expression of Recombinant Envelope Protein of Japanese Encephalitis Virus YL Strain in Escherichia coli Possesses Hemagglutination Activity

    The nucleotide sequence of glycoprotein E of YL vaccine strain was cloned, sequenced and expressed in E. coli. Phylogenetic analysis of envelope (E) amino acid sequences of 18 JEVs in GenBank showed that the vacc...

    S.-O. Chen, T.-H. Tsai, T.-J. Chang, M.-L. Wong, H.-P. Su, J.-J. Liu in Virus Genes (2004)

  7. No Access

    Article

    Cloning and Sequencing of Complete cDNA of Japanese Encephalitis Virus YL Strain in Taiwan

    We determined the complete nucleotide sequence of the YL strain of Japanese encephalitis virus and its amino acid sequence was deduced. Our results displayed that the genome of YL strain contained a single ope...

    J.-J. Liu, T.-H. Tsai, T.-J. Chang, M.-L. Wong in Virus Genes (2003)