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  1. Article

    Open Access

    Nucleotide excision repair is a potential therapeutic target in multiple myeloma

    Despite the development of novel drugs, alkylating agents remain an important component of therapy in multiple myeloma (MM). DNA repair processes contribute towards sensitivity to alkylating agents and therefo...

    R Szalat, M K Samur, M Fulciniti, M Lopez, P Nanjappa, A Cleynen, K Wen in Leukemia (2018)

  2. No Access

    Article

    Current anti-myeloma therapies in renal manifestations of monoclonal light chain-associated Fanconi syndrome: a retrospective series of 49 patients

    We retrospectively reviewed 49 patients with light chain (LC) Fanconi syndrome (FS). Patients presented with chronic kidney disease (median estimated glomerular filtration rate (eGFR) of 33 ml/min/1.73 m2) and tu...

    M Vignon, V Javaugue, M P Alexander, K El-Karoui, A Karras, D Roos-Weil in Leukemia (2017)

  3. No Access

    Article

    Consolidation with VTd significantly improves the complete remission rate and time to progression following VTd induction and single autologous stem cell transplantation in multiple myeloma

    X Leleu, G Fouquet, B Hebraud, M Roussel, D Caillot, M L Chrétien, B Arnulf in Leukemia (2013)

  4. No Access

    Article

    Impact of high-risk cytogenetics and prior therapy on outcomes in patients with advanced relapsed or refractory multiple myeloma treated with lenalidomide plus dexaméthasone

    This retrospective analysis investigated the prognostic value of del(13) and t(4;14) abnormalities and the impact of prior treatment on outcomes in 207 heavily pretreated patients with relapsed or refractory m...

    H Avet-Loiseau, J Soulier, J-P Fermand, I Yakoub-Agha, M Attal, C Hulin in Leukemia (2010)

  5. No Access

    Article

    Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma

    Multiple myeloma (MM) is a B-cell neoplasia caused by the proliferation of clonal plasma cells, primarily in the bone marrow (BM). The role of the BM microenvironment in the pathogenesis of the disease has bee...

    B Arnulf, S Lecourt, J Soulier, B Ternaux, M-Noelle Lacassagne, A Crinquette in Leukemia (2007)

  6. No Access

    Article

    Fludarabine plus cyclophosphamide in Waldenström's macroglobulinemia: results in 49 patients

    Fludarabine (FDR) therapy gives a response rate of about 30% in previously treated patients with Waldenström's macroglobulinemia (WM). The combination of FDR and cyclophosphamide (Cy) has been shown to be effe...

    J Tamburini, V Lévy, C Chaleteix, J P Fermand, A Delmer, L Stalniewicz, P Morel in Leukemia (2005)