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Article
Open AccessImpact of pro-domain stability of matrix metalloproteinase-8 on the outcome of sepsis
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Article
Open AccessABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1
ABL gene translocations create constitutively active tyrosine kinases that are causative in chronic myeloid leukemia, acute lymphocytic leukemia and other hematopoietic malignancies. Consistent retention of ABL S...
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Article
The effects of glucose ingestion and glucose regulation on memory performance in older adults with mild cognitive impairment
Previous research investigating the impact of glucose ingestion and/or improvements in glucose regulation has found selective cognitive facilitation on episodic memory tasks in successful ageing and dementia. ...
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Article
Abstracts of original contributions ASNC 2004 9th annual scientific session September 3-–October 3, 2004 New York, New York
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Article
Dissection of signaling pathways and cloning of new signal transducers in tyrosine kinase-induced pathways by genetic selection
We used genetic strategies which have been proven valuable to decipher signaling pathways in comparatively simple organisms such as Drosophila and Caenorhabditis elegans, to dissect signaling network activated...
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Article
Dissection of signaling pathways and cloning of new signal transducers in tyrosine kinase-induced pathways by genetic selection
We used genetic strategies which have been proven valuable to decipher signaling pathways in comparatively simple organisms such as Drosophila and Caenorhabditis elegans, to dissect signaling network activated...
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Article
Correlation between the orbital and intraocular portions of the optic nerve in glaucomatous and ocular hypertensive eyes
Background/Purpose It has recently been reported that the retrobulbar optic nerve diameter (OND) and cross-sectional area (ONCSA) are reduced in glaucoma. This study was performed to investigate the correlation b...
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Article
Evaluation of optic disc cup** using high-resolution ocular ultrasound
Background/Purpose The new Biovision B-Scan Probe has greater resolution than its predecessors because of its posteriorly placed focus (25 mm inside the eye) and the consequent reduction in size of the sound fiel...
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Chapter and Conference Paper
A Cloning Strategy to Identify Genes that Functionally Interact with Bcr-Abl for Transformation
We have developed an expression cloning system to identify genes which functionally interact with Bcr-Abl for transformation. This system is based on a complementation strategy we used recently to define the s...
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Article
The sensory neuropathy of Friedreich's ataxia: an autopsy study of a case with prolonged survival
Observations have been made on a patient with Friedreich's ataxia who died 52 years after the onset of symptoms. The pathology of the brain and spinal cord was typical of this disorder. Apart from loss of dors...
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Chapter and Conference Paper
Molecular Cloning and Serological Characterization of an Altered c-abl Gene Product Produced in Ph 1 CML Patients
The reciprocal translocation between human chromosomes 9 and 22, termed the Philadelphia chromosome (Ph 1), is observed in more than 90% of patients with chronic myelogenous leukemia. This translo...
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Article
311 Thyroid Antibodies and HL-A Antigens in Children with Thyroid Disease
Antibodies to thyroid cytoplasm (T.C.A.), to thyroid nuclei (ANA) and to thyroglobulin (T.G.A.) were determined in 30 children with thyrotoxicosis (Tx), in 13 with euthyroid goiter (EG), in 9 with hypothyroidi...
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Article
877 Muscle Carnitine Deficiency in a Patient with Persistent Neonatal Diabetes and Hypokalemia
A 3 year old Cuban female with persistent neonatal diabetes mellitus developed corneal opacities, photophobia, hirsuitism and failure to thrive following a prolonged episode of hypoglycemia with coma and seizu...