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  1. No Access

    Article

    The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes

    In order to obtain a comprehensive picture of the molecular events regulating cutaneous photodamage of intact human epidermis, suction blister roofs obtained after a single dose of in vivo ultraviolet (UV)B expos...

    C D Enk, J Jacob-Hirsch, H Gal, I Verbovetski, N Amariglio, D Mevorach… in Oncogene (2006)

  2. No Access

    Article

    The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation

    The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, participate in the retention of acute myeloblastic leukemia (AML) cells within the bone marrow microenvironment and their release in...

    S Tavor, M Eisenbach, J Jacob-Hirsch, T Golan, I Petit, K BenZion, S Kay… in Leukemia (2008)

  3. No Access

    Article

    Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target

    Wilms’ tumor (WT), the most frequent renal solid tumor in children, has been linked to aberrant Wnt signaling. Herein, we demonstrate that different WTs can be grouped according to either sensitivity or resist...

    N Pode-Shakked, O Harari-Steinberg, Y Haberman-Ziv, E Rom-Gross, S Bahar… in Oncogene (2011)

  4. No Access

    Article

    Modeling ductal carcinoma in situ: a HER2–Notch3 collaboration enables luminal filling

    A large fraction of ductal carcinoma in situ (DCIS), a non-invasive precursor lesion of invasive breast cancer, overexpresses the HER2/neu oncogene. The ducts of DCIS are abnormally filled with cells that evade a...

    C-R Pradeep, W J Köstler, M Lauriola, R Z Granit, F Zhang, J Jacob-Hirsch… in Oncogene (2012)

  5. No Access

    Article

    Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions

    The HER2/neu oncogene encodes a receptor-like tyrosine kinase whose overexpression in breast cancer predicts poor prognosis and resistance to conventional therapies. However, the mechanisms underlying aggressi...

    C-R Pradeep, A Zeisel, W J Köstler, M Lauriola, J Jacob-Hirsch, B Haibe-Kains… in Oncogene (2012)

  6. No Access

    Article

    Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes

    Skin carcinogenesis is known to be a multi-step process with several stages along its malignant evolution. We hypothesized that transformation of normal epidermis to cutaneous squamous cell carcinoma (cSCC) is...

    A Mizrahi, A Barzilai, D Gur-Wahnon, I Z Ben-Dov, S Glassberg, T Meningher… in Oncogene (2018)

  7. Article

    Correction: Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions

    C. -R Pradeep, A. Zeisel, W. J. Köstler, M. Lauriola, J. Jacob-Hirsch… in Oncogene (2024)

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