28 Result(s)

Article

The QUILT study: quilting sutures in patients undergoing breast cancer surgery: a stepped wedge cluster randomized trial study

Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires tr...

L. J. van Zeelst, B. ten Wolde, J. D. J. Plate, J. H. Volders… in BMC Cancer (2023)

Article

Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk (“ugly”) locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT)

The presence of mesorectal fascia (MRF) invasion, grade 4 extramural venous invasion (EMVI), tumour deposits (TD) or extensive or bilateral extramesorectal (lateral) lymph nodes (LLN) on MRI has been suggested...

K. van den Berg, D. P. Schaap, E. L. K. Voogt, T. E. Buffart… in BMC Cancer (2022)

Article

Body composition and its association with fatigue in the first 2 years after colorectal cancer diagnosis

Persistent fatigue among colorectal cancer (CRC) patients might be associated with unfavorable body composition, but data are sparse and inconsistent. We studied how skeletal muscle index (SMI), skeletal muscl...

H. van Baar, M. J. L. Bours, S. Beijer, M. van Zutphen… in Journal of Cancer Survivorship (2021)

Article

The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture

The tumour microenvironment (TME) forms a major obstacle in effective cancer treatment and for clinical success of immunotherapy. Conventional co-cultures have shed light onto multiple aspects of cancer immuno...

S. Di Blasio, G. F. van Wigcheren, A. Becker, A. van Duffelen… in Nature Communications (2020)

Article

De-escalation of axillary surgery in breast cancer patients treated in the neoadjuvant setting: a Dutch population-based study

An overall trend is observed towards de-escalation of axillary surgery in patients with breast cancer. The objective of this study was to evaluate this trend in patients treated with neoadjuvant systemic thera...

J. M. Simons, L. B. Koppert, E. J. T. Luiten… in Breast Cancer Research and Treatment (2020)

Article

MRI response rate after short-course radiotherapy on rectal cancer in the elderly comorbid patient: results from a retrospective cohort study

The aim of the present study was to evaluate MRI response rate and clinical outcome of short-course radiotherapy (SCRT) on rectal cancer as an alternative to chemoradiotherapy in patients where downstaging is ...

T. Koëter, S. G. C. van Elderen, G. F. A. J. B. van Tilborg… in Radiation Oncology (2020)

Article

Major differences in follow-up practice of patients with colorectal cancer; results of a national survey in the Netherlands

The precise content and frequency of follow-up of patients with colorectal cancer (CRC) is variable and guideline adherence is low. The aim of this study was to assess the view of colorectal surgeons on their ...

S. M. Qaderi, N. A. T. Wijffels, A. J. A. Bremers, J. H. W. de Wilt in BMC Cancer (2020)

Article

Metastatic behavior and overall survival according to breast cancer subtypes in stage IV inflammatory breast cancer

Distant metastatic disease is frequently observed in inflammatory breast cancer (IBC), with a poor prognosis as a consequence. The aim of this study was to analyze the association of hormone receptor (HR) and ...

D. J. P. van Uden, M. C. van Maaren, L. J. A. Strobbe, P. Bult… in Breast Cancer Research (2019)

Article

Low radiographic muscle density is associated with lower overall and disease-free survival in early-stage colorectal cancer patients

In cancer patients with a poor prognosis, low skeletal muscle radiographic density is associated with higher mortality. Whether this association also holds for early-stage cancer is not very clear. We aimed to...

Harm van Baar, S. Beijer, M. J. L. Bours… in Journal of Cancer Research and Clinical On… (2018)

Article

Study protocol of the CORRECT multicenter trial: the efficacy of blended cognitive behavioral therapy for reducing psychological distress in colorectal cancer survivors

Approximately one third of the colorectal cancer survivors (CRCS) experience high levels of psychological distress. Common concerns experienced by CRCS include distress related to physical problems, anxiety, f...

L. Leermakers, S. Döking, B. Thewes, A. M. J. Braamse, M. F. M. Gielissen… in BMC Cancer (2018)

Article

Impact of Centralizing Gastric Cancer Surgery on Treatment, Morbidity, and Mortality

Centralization of gastric cancer surgery is thought to improve outcome and has been imposed in the Netherlands since 2012. This study analyzes the effect of centralization in terms of treatment outcome and sur...

S. D. Nelen, L. Heuthorst, R. H. A. Verhoeven… in Journal of Gastrointestinal Surgery (2017)

Article

Increasing survival gap between young and elderly gastric cancer patients

This study investigates the treatment and survival of young versus elderly potentially curable gastric cancer patients in the Netherlands.

S. D. Nelen, R. H. A. Verhoeven, V. E. P. P. Lemmens, J. H. W. de Wilt… in Gastric Cancer (2017)

Article

Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08)

Studies showed that axillary lymph node dissection can be safely omitted in presence of positive sentinel lymph node(s) in breast cancer patients treated with breast conserving therapy. Since the outcome of th...

L. M. van Roozendaal, M. L. G. Vane, T. van Dalen, J. A. van der Hage… in BMC Cancer (2017)

Article

High tie versus low tie in rectal surgery: comparison of anastomotic perfusion

Both “high tie” (HT) and “low tie” (LT) are well-known strategies in rectal surgery. The aim of this study was to compare colonic perfusion after HT to colonic perfusion after LT.

Niels Komen, Juliette Slieker, Peter de Kort… in International Journal of Colorectal Disease (2011)

Article

Erratum to: High tie versus low tie in rectal surgery: comparison of anastomotic perfusion

Niels Komen, Juliette Slieker, Peter de Kort… in International Journal of Colorectal Disease (2011)