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Article
Bestimmung kleiner Eisenmengen
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Article
Untersuchung von Milch und Molkereiprodukten
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Article
Report on the expedition to Sardinia, 1953
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Article
Measurements of Electrical Potential for detecting Crack Extension in COD Tests
THE crack opening displacement (COD) test is currently being used by a large number of research establishments throughout Britain and the USA to establish the fracture characteristics of high toughness–low str...
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Article
A genetic and biochemical study of streptomycin-and spectinomycin-resistance in Salmonella typhimurium
In Salmonella typhimurium, streptomycin resistance can occur by mutation at the strA or the strB mutants have altered ribosomes which are refractory to the drug in cell-free amino acid incorporation systems, and ...
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Article
Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid
L-GLUTAMIC acid is probably an excitatory transmitter of major significance in the mammalian central nervous system1. The L-glutamic acid molecule is relatively flexible, and in an attempt to gain some insight in...
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Article
Functional and morphological effects of hypophysectomy and androgen replacement in the rabbit epididymis
The fertilizing ability of spermatozoa from the distal corpus epididymidis of 55 male rabbits of proven fertility has been determined after artificial insemination 1, 2, 3, 5, 7, and 11 days after hypophysecto...
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Article
Opiate agonist-antagonist effects on Renshaw cells and spinal interneurones
ANALGESIC doses of morphine change the levels1,2 and release3,4 of acetylcholine from the central nervous system. At the single neurone level, however, little is known of the effects of morphine on cholinergic tr...
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Article
Changes in amino acid sensitivity during polypeptide ‘desensitisation’
CURRENT interest in polypeptides as neurotransmitter substances in the central nervous system (CNS) has been focused on their ability to depolarise motoneurones1 and to excite single cells in various parts of the...
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Article
Effects of enkephalin and morphine on Renshaw cells in feline spinal cord
IT has been suggested that enkephalin is the endogenous ligand for the opiate receptor1–3. This substance is unevenly distributed throughout the brain3,4 and occurs as two pentapeptides—met- and leu-enkephalin5. ...
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Chapter and Conference Paper
Transposable Neomycin Phosphotransferases
Transposable genetic elements are discrete DNA segments with the capacity to move between independent DNA replicons within the cell. The recent discoveries that certain plasmid-borne genes, which confer resist...
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Article
Substance P and opiate receptors
IT has recently been demonstrated that the undecapeptide substance P (SP) produces analgesia in mice when administered intracerebroventricularly (i.v.) or intraperitoneally (i.p.)1. This effect of SP was reversed...
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Article
D-α-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones
THE identification of either L-glutamate or L-aspartate as excitatory transmitters in the mammalian central nervous system would be facilitated by the discovery of specific antagonists of amino acid-induced an...
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Article
Effects of D-α-aminoadipate on physiologically evoked responses of cat dorsal horn neurones
Microelectrophoretic administration of D-α-aminoadipate reversibly reduced excitatory responses of cat dorsal horn neurones evoked by iontophoretic glutamate and non-noxious peripheral stimuli but did not infl...
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Article
Conformational aspects of the actions of some piperidine dicarboxylic acids at excitatory amino acid receptors in the mammalian and amphibian spinal cord
A series of piperidine dicarboxylates (PDA) have been tested for excitatory amino acid agonist and antagonist activity and for synaptic depressant properties in the spinal cords of frogs and immature rats in v...
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Chapter
Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System
Current ideas are described on the classification of excitatory amino acid receptors in the mammalian central nervous system. The actions of some new agonists and antagonists for NMA receptors and non-NMA rece...
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Chapter
Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System
Current ideas are described on the classification of excitatory amino acid receptors in the mammalian central nervous system. The actions of some new agonists and antagonists for NMA receptors and non-NMA rece...
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Article
Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord
Three excitatory amino acid antagonists, 2-amino-5-phosphonovalerate (APV), γ-D-glutamyl-glycine (γDGG) and cis-2,3-piperidine dicarboxylate (PDA) have been compared with respect to their ability to block the ...
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Article
Decay rates and nitrogen dynamics of decomposing watercress (Nasturtium officinale R.Br.)
We examined the decomposition of watercress in the laboratory at 10° and 20 °C, and in the field. Rates varied from 0.058 g g−1 day−1 in the laboratory to 0.115 g g−1 day−1 in the field. There was a rapid generat...
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Article
Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro
Human lymphoid cells of LAZ-007 cell line, incubated with 10−4 to 10−6 molar of eight different organochlorine pesticides had dose related cytotoxicity, mitotic depression and cell cycle traverse inhibition. In c...
