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  1. Article

    Open Access

    Erratum: Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy

    Correction to: British Journal of Cancer (2009) 100, 1889–1895. doi:10.1038/sj.bjc.6605093 Owing to an error during typesetting, the name of the third author, Richard Morgan, was omitted from this paper when f...

    M Ismail, S Bokaee, R Morgan, J Davies, K J Harrington… in British Journal of Cancer (2009)

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  2. Article

    Open Access

    Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy

    Aquaporins (AQPs) are intrinsic membrane proteins that facilitate selective water and small solute movement across the plasma membrane. In this study, we investigate the role of inhibiting AQPs in sensitising pro...

    M Ismail, S Bokaee, J Davies, K J Harrington, H Pandha in British Journal of Cancer (2009)

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  3. No Access

    Article

    Salvage cryosurgery for locally recurrent prostate cancer following radiotherapy

    The popularity of radiotherapy as a minimally invasive treatment for prostate cancer is increasing. Despite advancements in radiation delivery, a number of patients will fail treatment. Salvage radical prostat...

    S Ahmed, B Lindsey, J Davies in Prostate Cancer and Prostatic Diseases (2005)

  4. Article

    Open Access

    Requirement for expert histopathological assessment of ovarian cancer and borderline tumours

    The distinction between borderline ovarian tumours (BOT) and ovarian carcinoma is made by histopathological assessment. Of 64 patients managed according to institutional BOT protocols, 27 (42%) had been referr...

    P S Sengupta, J H Shanks, C H Buckley, W D J Ryder, J Davies… in British Journal of Cancer (2000)

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  5. No Access

    Article

    Characterization and immunogenicity of a candidate subunit vaccine against varicella-zoster virus

    This study describes the properties of an inactivated subunit antigen preparation from varicella-zoster virus (VZV)-infected MRC-5 cells by treatment with detergent and formaldehyde, ultracentrifugation over s...

    J. Davies, J. A. Hallworth, P. McLeish, S. Randall… in Medical Microbiology and Immunology (1994)

  6. No Access

    Chapter

    Monocyte Chemotactic Peptide-1 (Mcp-1) and NAP-1/IL-8 Formation in Baboon Septicemia are Partially TNF Dependent

    Cytokines like IL-1 and IL-6 are released in sepsis in a TNF dependent manner. Therefore we asked the question, whether TNF might be responsible for MCP-1 and NAP-1 production in baboon septicemia (2 hours inf...

    H. Redl, G. Schlag, E. Paul, B. Strieter, S. Kunkel, M. Ceska, J. Davies… in The Chemokines (1993)

  7. No Access

    Chapter and Conference Paper

    The Role of TNF in Gram-Negative Sepsis in Baboon

    During sepsis TNF message is expressed and the protein is released both locally and into plasma. Teleologically such cytokine response must be beneficial to the host. However, from a certain threshold level of...

    H. Redl, G. Schlag G, J. Davies, W. A. Buurman… in Shock, Sepsis, and Organ Failure (1993)

  8. No Access

    Chapter and Conference Paper

    Trauma and Cytokines

    Trauma still constitutes the most frequent cause of death in the first four decades of life and ranks third over all age brackets (Baker et al. 1980, Baue 1990, Chaudry et al. 1990, National Safety Council 198...

    G. Schlag, H. Redl, S. Bahrami, J. Davies, P. Smuts… in Shock, Sepsis, and Organ Failure (1993)

  9. No Access

    Chapter

    Experiments with Kainate and Quisqualate Agonists and Antagonists in Relation to the Sub-Classification of ‘Non-NMDA’ Receptors

    The differentiation of “kainate” (K) and “quisqualate” (Q) sub-classes of non-NMDA excitatory amino acid (EAA) (Davies et al., 1979; Watkins, 1978) receptors was originally based on the selective depressant ac...

    J. C. Watkins, P. C. K. Pook, D. C. Sunter… in Excitatory Amino Acids and Neuronal Plasti… (1990)

  10. No Access

    Article

    Changes in strength and cross sectional area of the elbow flexors as a result of isometric strength training

    Changes in strength and size of the elbow flexor muscles have been compared during six weeks of isometric strength training in six male and six female subjects. Isometric training of one arm resulted in a sign...

    J. Davies, D. F. Parker, O. M. Rutherford… in European Journal of Applied Physiology and… (1988)

  11. No Access

    Article

    Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro

    Human lymphoid cells of LAZ-007 cell line, incubated with 10−4 to 10−6 molar of eight different organochlorine pesticides had dose related cytotoxicity, mitotic depression and cell cycle traverse inhibition. In c...

    R. C. Sobti, A. Krishan, J. Davies in Archives of Toxicology (1983)

  12. No Access

    Article

    Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord

    Three excitatory amino acid antagonists, 2-amino-5-phosphonovalerate (APV), γ-D-glutamyl-glycine (γDGG) and cis-2,3-piperidine dicarboxylate (PDA) have been compared with respect to their ability to block the ...

    J. Davies, Dr. J. C. Watkins in Experimental Brain Research (1983)

  13. No Access

    Chapter

    Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System

    Current ideas are described on the classification of excitatory amino acid receptors in the mammalian central nervous system. The actions of some new agonists and antagonists for NMA receptors and non-NMA rece...

    J. Davies, R. H. Evans, A. W. Jones, K. N. Mewett, D. A. S. Smith… in Excitotoxins (1983)

  14. No Access

    Article

    Conformational aspects of the actions of some piperidine dicarboxylic acids at excitatory amino acid receptors in the mammalian and amphibian spinal cord

    A series of piperidine dicarboxylates (PDA) have been tested for excitatory amino acid agonist and antagonist activity and for synaptic depressant properties in the spinal cords of frogs and immature rats in v...

    J. Davies, R. H. Evans, A. A. Francis, A. W. Jones… in Neurochemical Research (1982)

  15. No Access

    Article

    Functional and morphological effects of hypophysectomy and androgen replacement in the rabbit epididymis

    The fertilizing ability of spermatozoa from the distal corpus epididymidis of 55 male rabbits of proven fertility has been determined after artificial insemination 1, 2, 3, 5, 7, and 11 days after hypophysecto...

    M. C. Orgebin-Crist, J. Davies in Cell and Tissue Research (1974)