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Article

Radiosensitization by a novel Bcl-2 and Bcl-X_L inhibitor S44563 in small-cell lung cancer

Radiotherapy has a critical role in the treatment of small-cell lung cancer (SCLC). The effectiveness of radiation in SCLC remains limited as resistance results from defects in apoptosis. In the current study,...

Y Loriot, P Mordant, D Dugue, O Geneste, A Gombos, P Opolon… in Cell Death & Disease (2014)