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  1. Article

    Open Access

    Clonal diversity predicts persistence of SARS-CoV-2 epitope-specific T-cell response

    T cells play a pivotal role in reducing disease severity during SARS-CoV-2 infection and formation of long-term immune memory. We studied 50 COVID-19 convalescent patients and found that T cell response was in...

    Ksenia V. Zornikova, Alexandra Khmelevskaya, Savely A. Sheetikov… in Communications Biology (2022)

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  2. Article

    Open Access

    VDJviz: a versatile browser for immunogenomics data

    The repertoire of T- and B-cell receptor sequences encodes the antigen specificity of adaptive immunity system, determines its present state and guides its ability to mount effective response against encounter...

    Dmitriy V. Bagaev, Ivan V. Zvyagin, Ekaterina V. Putintseva, Mark Izraelson… in BMC Genomics (2016)

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  3. Article

    Open Access

    tcR: an R package for T cell receptor repertoire advanced data analysis

    The Immunoglobulins (IG) and the T cell receptors (TR) play the key role in antigen recognition during the adaptive immune response. Recent progress in next-generation sequencing technologies has provided an o...

    Vadim I. Nazarov, Mikhail V. Pogorelyy, Ekaterina A. Komech… in BMC Bioinformatics (2015)

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  4. No Access

    Article

    MiTCR: software for T-cell receptor sequencing data analysis

    Dmitriy A Bolotin, Mikhail Shugay, Ilgar Z Mamedov… in Nature Methods (2013)