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  1. Article

    Open Access

    Integrative assessment of brain and bone invasion in meningioma patients

    Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain invasion was included as an independent criterion in the re...

    Kerstin Zwirner, Frank Paulsen, Jens Schittenhelm, Irina Gepfner-Tuma in Radiation Oncology (2019)

  2. Article

    Open Access

    COX2 expression is associated with proliferation and tumor extension in vestibular schwannoma but is not influenced by acetylsalicylic acid intake

    Acetylsalicylic acid has been linked to a lower risk for different cancer types, presumably through its inhibitory effect on cyclooxygenase 2. This has also been investigated in vestibular schwannomas with pro...

    Felix Behling, Vanessa Ries, Marco Skardelly in Acta Neuropathologica Communications (2019)

  3. Article

    Open Access

    Sunitinib added to FOLFIRI versus FOLFIRI in patients with chemorefractory advanced adenocarcinoma of the stomach or lower esophagus: a randomized, placebo-controlled phase II AIO trial with serum biomarker program

    As a multi-targeted anti-angiogenic receptor tyrosine kinase (RTK) inhibitor sunitinib (SUN) has been established for renal cancer and gastrointestinal stromal tumors. In advanced refractory esophagogastric ca...

    Markus Moehler, Irina Gepfner-Tuma, Annett Maderer, Peter C. Thuss-Patience in BMC Cancer (2016)