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  1. Article

    Open Access

    Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer’s Disease

    Alzheimer’s disease is a neurodegenerative disorder clinically defined by gradual cognitive impairment and alteration in executive function. We conducted an epigenome-wide association study (EWAS) of a clinica...

    Ignazio S. Piras, Danielle Brokaw, Yinfei Kong… in Cellular and Molecular Neurobiology (2023)

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    Article

    Harsh Parenting Predicts Novel HPA Receptor Gene Methylation and NR3C1 Methylation Predicts Cortisol Daily Slope in Middle Childhood

    Adverse experiences in childhood are associated with altered hypothalamic–pituitary–adrenal (HPA) axis function and negative health outcomes throughout life. It is now commonly accepted that abuse and neglect ...

    Candace R. Lewis, Reagan S. Breitenstein… in Cellular and Molecular Neurobiology (2021)

  3. Article

    Open Access

    The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

    Achaete-scute homolog 1 gene (ASCL1) is a gene classifier for the proneural (PN) transcriptional subgroup of glioblastoma (GBM) that has a relevant role in the neuronal-like differentiation of GBM cancer stem cel...

    Ashwin Narayanan, Filippo Gagliardi, Alberto L. Gallotti… in Cell Death & Differentiation (2019)

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