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Article
Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia
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Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia
The TLX1 transcription factor is critically involved in the multi-step pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) and often cooperates with NOTCH1 activation during malignant T-cell transforma...
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Article
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
The MYB oncogene is a leucine zipper transcription factor essential for normal and malignant hematopoiesis. In T-cell acute lymphoblastic leukemia (T-ALL), elevated MYB levels can arise directly through T-cell re...