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Article
Open AccessEstablishment of tumor microenvironment-preserving organoid model from patients with intracranial meningioma
Although meningioma is the most common primary brain tumor, treatments rely on surgery and radiotherapy, and recurrent meningiomas have no standard therapeutic options due to a lack of clinically relevant rese...
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Article
Nocturnal systolic blood pressure dip** and progression of chronic kidney disease
The relationship between declining nocturnal blood pressure (BP) and adverse cardiovascular outcomes is well-recognized. However, the relationship between diurnal BP profile and the risk of chronic kidney dise...
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Article
Open AccessAssessment of nutrient adequacy in undergraduate students during the undertaking shipboard internship: using 12-day dietary recall through smartphone photography
This study aimed to investigated nutritional status and estimated the adequacy of dietary intake of university students during shipboard internships.
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Article
Open AccessCaveolin-1 mediates the utilization of extracellular proteins for survival in refractory gastric cancer
Despite advances in cancer therapy, the clinical outcome of patients with gastric cancer remains poor, largely due to tumor heterogeneity. Thus, finding a hidden vulnerability of clinically refractory subtypes...
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Article
Open AccessSocioeconomic burden of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa in Korea
We aimed to estimate the socioeconomic burden of pneumonia due to multidrug-resistant Acinetobacter baumannii (MRAB) and Pseudomonas aeruginosa (MRPA). We prospectively searched for MRAB and MRPA pneumonia cases ...
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Article
Open AccessDissection of molecular and histological subtypes of papillary thyroid cancer using alternative splicing profiles
Despite growing evidence of the relevance of alternative splicing (AS) to cancer development and progression, the biological implications of AS for tumor behaviors, including papillary thyroid cancer (PTC), re...
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Article
Open AccessElevated levels of urine isocitrate, hydroxymethylglutarate, and formiminoglutamate are associated with arterial stiffness in Korean adults
Recent evidence suggests that cellular perturbations play an important role in the pathogenesis of cardiovascular diseases. Therefore, we analyzed the association between the levels of urinary metabolites and ...
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Article
Open AccessDistinct genomic profiles of gestational choriocarcinoma, a unique cancer of pregnant tissues
Little is known about genomic alterations of gestational choriocarcinoma (GC), unique cancer that originates in pregnant tissues, and the progression mechanisms from the nonmalignant complete hydatidiform mole...
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Article
Open AccessBowel preparation for colonoscopy may decrease the levels of testosterone in Korean men
Although colonoscopy is commonly conducted for medical check-ups in Korea, investigations for the influence of bowel preparation on various health conditions are insufficient. This cross-sectional study invest...
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Article
Structured vs narrative reporting of pelvic MRI for fibroids: clarity and impact on treatment planning
To evaluate clarity and usefulness of MRI reporting of uterine fibroids using a structured disease-specific template vs. narrative reporting for planning of fibroid treatment by gynaecologists and intervention...
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Article
Open AccessMutational signatures and chromosome alteration profiles of squamous cell carcinomas of the vulva
Vulvar squamous cell carcinoma (SCC) consists of two different etiologic categories: human papilloma virus (HPV)-associated (HPV (+)) and HPV-non-associated (HPV (−)). There have been no genome-wide studies on...
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Chapter
Innumerable Fibroids
This case illustrates our approach to a patient with many uterine fibroids who desires future fertility. We tailor the surgical plan to each individual patient depending on one’s symptoms, age, anatomy, reprod...
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Article
Open AccessTwo helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium
Anoctamin 1 (ANO1)/TMEM16A is a Cl− channel activated by intracellular Ca2+ mediating numerous physiological functions. However, little is known of the ANO1 activation mechanism by Ca2+. Here, we demonstrate that...
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Article
Open AccessEpicardial fat thickness is associated to type 2 diabetes mellitus in Korean men: a cross-sectional study
Visceral fat, including epicardial fat (EF) is recognized as a responsible factor of cardiovascular disease. The aim of this study was to investigate the relationship between EF and diabetes in Korean men.
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Article
Open AccessTrends in receiving chemotherapy for advanced cancer patients at the end of life
The use of chemotherapy in advanced cancer patients has increased with the development of novel, high-efficacy anticancer therapeutic agents. In the current study, we analyzed the 10-year trends in patients re...
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Article
The association between genetic variants of RUNX2, ADIPOQ and vertebral fracture in Korean postmenopausal women
Contrary to the traditional belief that obesity acts as a protective factor for bone, recent epidemiologic studies have shown that body fat might be a risk factor for osteoporosis and bone fracture. Accordingl...
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Article
Open AccessSynchronous development of intrahepatic cholangiocarcinoma and hepatocellular carcinoma in different sites of the liver with chronic B-viral hepatitis: two case reports
Synchronous development of primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma has been reported rarely. In literature review, there have been only 35 reported cases of synchronous hepatocellu...
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Article
Open AccessVoluntary movements as a possible non-reflexive pain assay
The quantification of pain intensity in vivo is essential for identifying the mechanisms of various types of pain or for evaluating the effects of different analgesics. A variety of behavioral tests for pain meas...
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Article
Validity of using Fundamentals of Laparoscopic Surgery (FLS) program to assess laparoscopic competence for gynecologists
This study was designed to investigate the validity of using the Fundamentals of Laparoscopic Surgery (FLS) program to assess laparoscopic competence among gynecologists.
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Chapter and Conference Paper
Upper Airway and Abdominal Motor Output During Sneezing: Is the In Vivo Decererate Rat an Adequate Model?
While numerous studies have focused on identifying and characterizing the neural mechanisms mediating upper airway defense reflexes in the anesthetized or decerebrate adult cat, little is known about these beh...
