6 Result(s)
within
Huo Tan
Biomedicine
Cell Biology
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Article
Open AccessDecreased SATB1 expression promotes AML cell proliferation through NF-κB activation
Special AT-rich sequence-binding protein 1 (SATB1) is a chromatin-remodeling protein that regulates gene expressions in different types of cancer. Up-regulation of SATB1 is linked with progression of tumors. O...
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Article
Open AccessClinical and laboratory features of seven patients with acute myeloid leukemia (AML)-M2/M3 and elevated myeloblasts and abnormal promyelocytes
There is limited information on a special subtype of Acute myeloid leukemia (AML) characterized by >20% myeloblasts and >20% abnormal promyelocytes in bone marrow and peripheral blood.
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Article
Open AccessAbnormal expression of A20 and its regulated genes in peripheral blood from patients with lymphomas
Cell-mediated immunity is often suppressed in patients with hematological malignancies. Recently, we found that low T cell receptor (TCR)-CD3 signaling was related to abnormal expression of the negative regula...
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Article
Open AccessCorrelation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer
B7-H3 and matrix metalloproteinases 2 (MMP-2) are reported highly expressed in malignant tumor, we investigate the relationship between B7-H3 expression and MMP-2 on malignant behavior and prognosis predictabl...
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Article
Open AccessNotch1 signaling is involved in regulating Foxp3 expression in T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive hematologic malignancy. Immune tolerance induced by CD4+CD25+ regulatory T cells (Tregs) with high expression of Foxp3 is an important hypothesis...
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Article
Open AccessMutations increased overexpression of Notch 1 in T-cell acute lymphoblastic leukemia
The Notch signaling pathway is crucial in T-cell development, Notch 1 mutations are frequently present in T-cell acute lymphoblastic leukemia (T-ALL). To investigate the feature of Notch 1 mutation and its corres...
